Is Heptyl Butyrate safe in cosmetics?
Heptyl Butyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Heptyl Butyrate
Also known as: Heptyl butanoate, Butanoic acid, heptyl ester, BRN 1760253, Butyric acid, heptyl ester, EINECS 227-526-5 (+2 more)
INCI: HEPTYL BUTYRATE
Heptyl Butyrate (CAS 5870-93-9) is a cosmetic cosmetic ingredient functioning as Fragrance / flavoring agent with fruity, chamomile-like odor. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 5870-93-9 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance / flavoring agent with fruity, chamomile-like odor
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
heptyl butanoate
InChIKey
JPQHLIYIQARLQM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA 2549 (GRAS)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Heptyl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 675 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
154
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
HEPTYL BUTYRATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Heptyl Butyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Heptyl butanoate
Butanoic acid, heptyl ester
BRN 1760253
Butyric acid, heptyl ester
EINECS 227-526-5
FEMA No. 2549
UNII-6YF38H29F1
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
active_ingredient; Pesticides
active_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3186512
Frequently Asked Questions
Is Heptyl Butyrate allowed in the EU?
Heptyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Heptyl Butyrate do in cosmetics?
Heptyl Butyrate functions as: Fragrance / flavoring agent with fruity, chamomile-like odor. It is classified as a cosmetic ingredient in our database. CAS number: 5870-93-9.
Is Heptyl Butyrate used outside cosmetics?
Heptyl Butyrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Heptyl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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