NOAEL Data Cosmetic Ingredient

Heptyl butyrate

Also known as: Heptyl butanoate, Butanoic acid, heptyl ester, BRN 1760253, Butyric acid, heptyl ester, EINECS 227-526-5 (+2 more)

CAS 5870-93-9

Heptyl butyrate (CAS 5870-93-9) is a chemical substance. Key regulatory status: 14 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Heptyl Butyrate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields

Name

Heptyl butyrate

CAS Number

5870-93-9

DTXSID

DTXSID0042038

Molecular Formula

C11H22O2

InChI Key

JPQHLIYIQARLQM-UHFFFAOYSA-N

Monoisotopic Mass

186.16198

Synonyms

Heptyl butanoateButanoic acid, heptyl esterBRN 1760253Butyric acid, heptyl esterEINECS 227-526-5FEMA No. 2549UNII-6YF38H29F1

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records

FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 14 records

List	Keyword	Source
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	California Department of Pesticide Regulation	State of California
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
IFRA Transparency	IFRA	IFRA
Europe	European Commission	Fl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 24 of 24 studies

Value	Unit	Endpoint	Route	Species	Source
6YF38H29F1	UNII	FDA UNII substance identifier	-	-	openFDA substances
6YF38H29F1	UNII	FDA UNII substance identifier	-	-	openFDA substances
6YF38H29F1	UNII	FDA UNII substance identifier	-	-	openFDA substances
6YF38H29F1	UNII	FDA UNII substance identifier	-	-	openFDA substances
-	%	Incidence of positive responses	Dermal	Human	NTP_ICE_skin_sensitization
675	ug/cm2	Induction dose per skin area	Dermal	Human	NTP_ICE_skin_sensitization
-	unitless	Model Score	-	-	NTP_ICE_endocrine
-	%	Positive reaction	Dermal	Human	NTP_ICE_skin_irritation
3	unitless	Relative reliability score	Dermal	Human	NTP_ICE_skin_sensitization
92.28	%	Viability	Dermal	-	NTP_ICE_skin_irritation
98.67	%	Viability	Dermal	-	NTP_ICE_skin_irritation
100.48	%	Viability	Dermal	-	NTP_ICE_skin_irritation
102.1	%	Viability	Dermal	-	NTP_ICE_skin_irritation
102.32	%	Viability	Dermal	-	NTP_ICE_skin_irritation
103.99	%	Viability	Dermal	-	NTP_ICE_skin_irritation
104.9	%	Viability	Dermal	-	NTP_ICE_skin_irritation
105.9	%	Viability	Dermal	-	NTP_ICE_skin_irritation
108.8	%	Viability	Dermal	-	NTP_ICE_skin_irritation
109.3	%	Viability	Dermal	-	NTP_ICE_skin_irritation
109.7	%	Viability	Dermal	-	NTP_ICE_skin_irritation
109.8	%	Viability	Dermal	-	NTP_ICE_skin_irritation
111.54	%	Viability	Dermal	-	NTP_ICE_skin_irritation
112.2	%	Viability	Dermal	-	NTP_ICE_skin_irritation
118.8	%	Viability	Dermal	-	NTP_ICE_skin_irritation

Showing 24 of 24 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3186512

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for Heptyl butyrate?

Heptyl butyrate has 24 NOAEL studies in the database. The lowest reported value is 6YF38H29F1 UNII. Source: openFDA substances.

What regulatory lists include Heptyl butyrate?

Heptyl butyrate appears on 5 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, IFRA Transparency, and 2 more. Source: EPA CPDat.

Is Heptyl butyrate used in cosmetics?

Yes, Heptyl butyrate is also indexed as a cosmetic ingredient under the name Heptyl Butyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Heptyl butyrate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is Heptyl butyrate used outside industrial chemicals?

Heptyl butyrate also appears in cosmetics, pharmaceutical, food safety databases.