Ginseng Extract (Panax Ginseng Root Extract)

INCI: PANAX GINSENG ROOT EXTRACT

Ginseng Extract (Panax Ginseng Root Extract) (CAS 84650-12-4) is a cosmetic active ingredient functioning as Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 84650-12-4 →

Auto-generated CPSR Part A draft with source citations
Function
Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.
Safety Rating
GOOD

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted without restriction. Strong market presence in K-beauty and premium anti-aging segments. Topical ginsenoside efficacy supported by in-vitro and some clinical data. MoCRA safety substantiation required.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ginseng Extract (Panax Ginseng Root Extract).

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

4 property records from structured ingredient metadata.

acne
{"cas_number": "84650-12-4", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "5-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restrictio…
anti_aging
{"anti_aging_claim": "anti-wrinkle, firming, antioxidant-protection", "mechanism_of_action": "Ginsenosides, saponins", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "Mild", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytotherapy Researc…
anti_pollution
{"cas_number": "90045-38-8", "ingredient_class": "Nrf2_activator", "primary_mechanism": "enzyme_induction", "pollution_types_targeted": "PM2_5/UV_A/ozone", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no",…
self_tanning
{"cas_number": "90045-38-8", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "A…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant Deodorizer Humectant Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Ginseng Extract (Panax Ginseng Root Extract).

Regulatory Flags

adaptogen antioxidant anti-aging collagen-synthesis k-beauty holistic-beauty mmp-inhibitor

Chemical Function

Humectant Softener and conditioner Antioxidant Deodorizer

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Ginseng Extract (Panax Ginseng Root Extract) safe in cosmetics?

Ginseng Extract (Panax Ginseng Root Extract) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Ginseng Extract (Panax Ginseng Root Extract) allowed in the EU?

Ginseng Extract (Panax Ginseng Root Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginseng Extract (Panax Ginseng Root Extract) do in cosmetics?

Ginseng Extract (Panax Ginseng Root Extract) functions as: Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.. It is classified as a Active Ingredient in our database. CAS number: 84650-12-4.

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