What is the NOAEL for D-Fructose-1,6-diphosphate?
D-Fructose-1,6-diphosphate has 4 NOAEL studies in the database. The lowest reported value is M7522JYX1H UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
D-Fructose-1,6-diphosphate
Also known as: Diphosphofructose, Fosfructose, Esafosfan, EINECS 207-683-6, Fructose-1,6-bisphosphate (+7 more)
CAS 488-69-7
D-Fructose-1,6-diphosphate (CAS 488-69-7) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
D-Fructose-1,6-diphosphate
CAS Number
488-69-7
DTXSID
DTXSID0048347
Molecular Formula
C6H14O12P2
InChI Key
RNBGYGVWRKECFJ-ARQDHWQXSA-N
Monoisotopic Mass
339.99605
Synonyms
DiphosphofructoseFosfructoseEsafosfanEINECS 207-683-6Fructose-1,6-bisphosphateHarden-Young-EsterD-arabino-2-Hexulose-1,6-bis(dihydrogenphosphat)UNII-M7522JYX1H1,6-di-O-phosphono-beta-D-fructofuranose[(2R,3S,4R,5R)-2,3,4-trihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]methoxyphosphonic acid[(2R,3S,4R,5R)-2,3,4-trihydroxy-5-(phosphonooxymethyl)tetrahydrofuran-2-yl]methoxyphosphonic acidbeta-D-fructofuranose 1,6-bisphosphate
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | US International Trade Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| M7522JYX1H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M7522JYX1H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M7522JYX1H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M7522JYX1H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1235112
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include D-Fructose-1,6-diphosphate?
D-Fructose-1,6-diphosphate appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is D-Fructose-1,6-diphosphate used in cosmetics?
Yes, D-Fructose-1,6-diphosphate is also indexed as a cosmetic ingredient under the name Fructose Bisphosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for D-Fructose-1,6-diphosphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is D-Fructose-1,6-diphosphate used outside industrial chemicals?
D-Fructose-1,6-diphosphate also appears in cosmetics, pharmaceutical databases.