Is Eugenyl Phenylacetate safe in cosmetics?
Eugenyl Phenylacetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Eugenyl Phenylacetate
INCI: EUGENYL PHENYLACETATE
Eugenyl Phenylacetate (CAS 10402-33-2) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 10402-33-2 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2-methoxy-4-prop-2-enylphenyl) 2-phenylacetate
InChIKey
JEEUACXJJPNYOL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific 21 CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Eugenyl Phenylacetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
NESIL
8100 µg/cm²
GHS: 1B
Human: positive
Source: HPPT: [85] Epstein WL (1976): Reports to RIFM, 30 March and 27 May, unpublished.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 8100 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Eugenyl Phenylacetate.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3187535
Frequently Asked Questions
Is Eugenyl Phenylacetate allowed in the EU?
Eugenyl Phenylacetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Eugenyl Phenylacetate do in cosmetics?
Eugenyl Phenylacetate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 10402-33-2.
Is Eugenyl Phenylacetate used outside cosmetics?
Eugenyl Phenylacetate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Eugenyl Phenylacetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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