What is the NOAEL for Eugenyl phenylacetate?
Eugenyl phenylacetate has 11 NOAEL studies in the database. The lowest reported value is 12 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
Eugenyl phenylacetate
Also known as: EINECS 233-868-6, Eugenol phenylacetate, NSC 133460
CAS 10402-33-2
Eugenyl phenylacetate (CAS 10402-33-2) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Eugenyl phenylacetate
CAS Number
10402-33-2
DTXSID
DTXSID0047406
Molecular Formula
C18H18O3
InChI Key
JEEUACXJJPNYOL-UHFFFAOYSA-N
Monoisotopic Mass
282.125594
Synonyms
EINECS 233-868-6Eugenol phenylacetateNSC 133460
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 19.2 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 12 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| T6KBF67K9F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T6KBF67K9F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T6KBF67K9F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T6KBF67K9F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3.125 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 8100 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 12960 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187535
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include Eugenyl phenylacetate?
Eugenyl phenylacetate appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is Eugenyl phenylacetate used in cosmetics?
Yes, Eugenyl phenylacetate is also indexed as a cosmetic ingredient under the name Eugenyl Phenylacetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Eugenyl phenylacetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Eugenyl phenylacetate used outside industrial chemicals?
Eugenyl phenylacetate also appears in cosmetics, pharmaceutical databases.