Is Ethyl Pyruvate safe in cosmetics?
Ethyl Pyruvate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ethyl Pyruvate
Also known as: EINECS 210-511-2, Ethyl acetylformate, Ethyl alpha-ketopropionate, Ethyl pyroracemate, FEMA No. 2457 (+1 more)
INCI: ETHYL PYRUVATE
Ethyl Pyruvate (CAS 617-35-6) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient; skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 617-35-6 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient; skin conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
ethyl 2-oxopropanoate
InChIKey
XXRCUYVCPSWGCC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not listed as prohibited or restricted under 21 CFR Parts 700/250
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Pyruvate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (5)
JECFA Number
938
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ETHYL ACETYLFORMATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/98 | FAS 48-JECFA 57/333
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ETHYL PYRORACEMATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/98 | FAS 48-JECFA 57/333
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ETHYL alpha-KETOPROPIONATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/98 | FAS 48-JECFA 57/333
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ETHYL PYRUVATE | 2001 | No safety concern at current levels of intake when used as a flavouring agent | TRS 909-JECFA 57/98 | FAS 48-JECFA 57/333
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Softener and conditioner
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Pyruvate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
EINECS 210-511-2
Ethyl acetylformate
Ethyl alpha-ketopropionate
Ethyl pyroracemate
FEMA No. 2457
UNII-03O98E01OB
Chemical Function
Softener and conditioner
Flavouring and nutrient
Fragrance
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ETHYL PYRUVATE
ChEMBL ID
CHEMBL173373
Max Phase
2
Frequently Asked Questions
Is Ethyl Pyruvate allowed in the EU?
Ethyl Pyruvate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Pyruvate do in cosmetics?
Ethyl Pyruvate functions as: Fragrance ingredient; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 617-35-6.
Is Ethyl Pyruvate used outside cosmetics?
Ethyl Pyruvate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ethyl Pyruvate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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