NOAEL Data REACH Registered Cosmetic Ingredient

Propanoic acid, 2-oxo-, ethyl ester

Also known as: EINECS 210-511-2, Ethyl acetylformate, Ethyl alpha-ketopropionate, Ethyl pyroracemate, FEMA No. 2457 (+1 more)

CAS 617-35-6

Propanoic acid, 2-oxo-, ethyl ester (CAS 617-35-6) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Ethyl Pyruvate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
Propanoic acid, 2-oxo-, ethyl ester
CAS Number
617-35-6
DTXSID
DTXSID2060674
Molecular Formula
C5H8O3
InChI Key
XXRCUYVCPSWGCC-UHFFFAOYSA-N
Monoisotopic Mass
116.047344
Synonyms
EINECS 210-511-2Ethyl acetylformateEthyl alpha-ketopropionateEthyl pyroracemateFEMA No. 2457UNII-03O98E01OB

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Softener and conditionerFlavouring and nutrientFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
Canada; pharmaceuticalDrugBankDrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
03O98E01OBUNIIFDA UNII substance identifier--openFDA substances
03O98E01OBUNIIFDA UNII substance identifier--openFDA substances
03O98E01OBUNIIFDA UNII substance identifier--openFDA substances
03O98E01OBUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredEthyl pyruvate210-511-2ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL ETHYL PYRUVATE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Propanoic acid, 2-oxo-, ethyl ester?

Propanoic acid, 2-oxo-, ethyl ester has 4 NOAEL studies in the database. The lowest reported value is 03O98E01OB UNII. Source: openFDA substances.

What regulatory lists include Propanoic acid, 2-oxo-, ethyl ester?

Propanoic acid, 2-oxo-, ethyl ester appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is Propanoic acid, 2-oxo-, ethyl ester used in cosmetics?

Yes, Propanoic acid, 2-oxo-, ethyl ester is also indexed as a cosmetic ingredient under the name Ethyl Pyruvate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Propanoic acid, 2-oxo-, ethyl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Propanoic acid, 2-oxo-, ethyl ester used outside industrial chemicals?

Propanoic acid, 2-oxo-, ethyl ester also appears in cosmetics, pharmaceutical, food safety, cannabis databases.