Is Dichlorobenzyl Alcohol safe in cosmetics?
Dichlorobenzyl Alcohol has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Dichlorobenzyl Alcohol
Also known as: 2,4-Dichlorobenzenemethanol, BRN 1448652, EINECS 217-210-5, Myacide SP, NSC 15635 (+3 more)
Dichlorobenzyl Alcohol (CAS 1777-82-8) is a cosmetic cosmetic ingredient functioning as Biocide; Preservative. NOAEL 100 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max 0.15%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1777-82-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Dichlorobenzyl Alcohol is classified GHS Danger (H318, H332, H412) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Biocide; Preservative
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2,4-dichlorophenyl)methanol
InChIKey
DBHODFSFBXJZNY-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
0.15%
US US Status
permitted
US Notes
Permitted with no specific CFR prohibition
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dichlorobenzyl Alcohol.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Dichlorobenzyl Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =100 mg/kg | - | rat | NOAEL study | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg/day | dermal | rabbit | irritation | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg | - | rat | NOAEL study | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg/day | dermal | rabbit | irritation | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg | - | rat | NOAEL study | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg/day | dermal | rabbit | irritation | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg | - | rat | NOAEL study | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg/day | dermal | rabbit | irritation | SCCNFP_vision_codex |
| NOAEL | =100 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =400 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Dichlorobenzyl Alcohol across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex V — Permitted Preservatives
Max: 0.15%
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: Preservative. Max: 0.15%. —
SA Saudi SFDA (V - Preservatives)
Max: 0.0015.
BRIN Brazil/India Cosmetics
Brazil: Permitted Preservative · max 0,15%
India: Permitted Preservative · max 0.0015
Additional Jurisdictional Restrictions (3)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | permitted_preservative | 0.15 | all cosmetics |
| BR | permitted_preservative | 0.15 | - |
| ASEAN | permitted_preservative | 0.15% | All products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Pharmaceutical
Preservative
Regulatory List Membership (2)
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Dichlorobenzyl Alcohol.
Regulatory Flags
preservative
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Dichlorobenzyl Alcohol by CAS number or substance name.
Studies
10
Lowest NOAEL
100
Highest NOAEL
400
Units vary across source rows: mg/kg bw/day, mg/kg, mg/kg/day
ToxValDB_ECHA_IUCLID
SCCNFP_vision_codex
Known Synonyms
2,4-Dichlorobenzenemethanol
BRN 1448652
EINECS 217-210-5
Myacide SP
NSC 15635
Rapidosept
UNII-1NKX3648J9
Dybenal
Chemical Function
Preservative
Pharmaceutical
Biocide
Regulatory Lists
Europe; Personal care
active_ingredient; Europe; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
DICHLOROBENZYL ALCOHOL
ChEMBL ID
CHEMBL3184437
Max Phase
-1
Frequently Asked Questions
Is Dichlorobenzyl Alcohol allowed in the EU?
Dichlorobenzyl Alcohol EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.
What does Dichlorobenzyl Alcohol do in cosmetics?
Dichlorobenzyl Alcohol functions as: Biocide; Preservative. It is classified as a cosmetic ingredient in our database. CAS number: 1777-82-8.
What is the NOAEL for Dichlorobenzyl Alcohol?
The NOAEL (No Observed Adverse Effect Level) for Dichlorobenzyl Alcohol is =100 mg/kg based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: SCCNFP_vision_codex.
Is Dichlorobenzyl Alcohol used outside cosmetics?
Dichlorobenzyl Alcohol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Dichlorobenzyl Alcohol have different safety status in cosmetics vs industrial chemicals?
Dichlorobenzyl Alcohol is classified GHS Danger (H318, H332, H412) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
Compliance Tools
Check Dichlorobenzyl Alcohol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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