What is the NOAEL for 2,4-Dichlorobenzyl alcohol?
2,4-Dichlorobenzyl alcohol has 19 NOAEL studies in the database. The lowest reported value is 100 mg/kg in rat. Source: UnifiedCodex:SCCNFP:beta.noael_studies.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,4-Dichlorobenzyl alcohol
Also known as: 2,4-Dichlorobenzenemethanol, BRN 1448652, EINECS 217-210-5, Myacide SP, NSC 15635 (+3 more)
CAS 1777-82-8
2,4-Dichlorobenzyl alcohol (CAS 1777-82-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
2,4-Dichlorobenzyl alcohol is classified GHS Danger (H318, H332, H412) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
19
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
2,4-Dichlorobenzyl alcohol
CAS Number
1777-82-8
DTXSID
DTXSID9041362
Molecular Formula
C7H6Cl2O
InChI Key
DBHODFSFBXJZNY-UHFFFAOYSA-N
Monoisotopic Mass
175.97957
Synonyms
2,4-DichlorobenzenemethanolBRN 1448652EINECS 217-210-5Myacide SPNSC 15635RapidoseptUNII-1NKX3648J9Dybenal
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
PreservativePharmaceuticalBiocide
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | European Commission | CosIng |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 19 of 19 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 100 | mg/kg | - | - | rat | UnifiedCodex:SCCNFP:beta.noael_studies |
| 100 | mg/kg | - | - | rat | UnifiedCodex:SCCNFP:beta.noael_studies |
| 1NKX3648J9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1NKX3648J9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1NKX3648J9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1NKX3648J9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 200 | mg/kg bw/day | LOAEL | oral | rat | COSMOS_DB |
| =100 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =100 | mg/kg | NOAEL | - | rat | SCCNFP_vision_codex |
| =100 | mg/kg/day | NOAEL | dermal | rabbit | SCCNFP_vision_codex |
| =100 | mg/kg | NOAEL | - | rat | SCCNFP_vision_codex |
| =100 | mg/kg/day | NOAEL | dermal | rabbit | SCCNFP_vision_codex |
| =100 | mg/kg | NOAEL | - | rat | SCCNFP_vision_codex |
| =100 | mg/kg/day | NOAEL | dermal | rabbit | SCCNFP_vision_codex |
| =100 | mg/kg | NOAEL | - | rat | SCCNFP_vision_codex |
| =100 | mg/kg/day | NOAEL | dermal | rabbit | SCCNFP_vision_codex |
| <200 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =400 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 100 | mg/kg/day | irritation | dermal | rabbit | UnifiedCodex:SCCNFP:beta.noael_studies |
Showing 19 of 19 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,4-dichlorobenzyl alcohol | 217-210-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.15%
Category
Preservative
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
DICHLOROBENZYL ALCOHOL
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include 2,4-Dichlorobenzyl alcohol?
2,4-Dichlorobenzyl alcohol appears on 2 regulatory/inventory lists including Europe; Personal care, active_ingredient; Europe; Pesticides. Source: EPA CPDat.
Is 2,4-Dichlorobenzyl alcohol used in cosmetics?
Yes, 2,4-Dichlorobenzyl alcohol is also indexed as a cosmetic ingredient under the name Dichlorobenzyl Alcohol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,4-Dichlorobenzyl alcohol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2,4-Dichlorobenzyl alcohol have different safety status in cosmetics vs industrial chemicals?
2,4-Dichlorobenzyl alcohol is classified GHS Danger (H318, H332, H412) in the chemicals database but is restricted in EU cosmetics at max 0.15%.
Is 2,4-Dichlorobenzyl alcohol used outside industrial chemicals?
2,4-Dichlorobenzyl alcohol also appears in cosmetics, pharmaceutical databases.