Moderate Cosmetic Ingredient NOAEL Data

Decanal

Also known as: BRN 1362530, EINECS 203-957-4, FEMA No. 2362, UNII-31Z90Q7KQJ, 1-Decanal (+6 more)

INCI: DECANAL

Decanal (CAS 112-31-2) is a cosmetic cosmetic ingredient functioning as Fragrance / Perfuming. Reported NOAEL =200 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 112-31-2 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance / Perfuming
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C10H20O
MW
156.26 g/mol
EC Number
203-957-4
PubChem CID
8175
IUPAC Name
decanal
InChIKey
KSMVZQYAVGTKIV-UHFFFAOYSA-N

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Allowed. Meets FCC specifications; GRAS for food use; permitted in cosmetics under FDA 21 CFR 117. Follows IFRA guidelines.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Decanal.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Decanal. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =200 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID
NOAEL =300 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

1 property record from structured ingredient metadata.

fragrance
{"cas_number": "112-31-2", "ingredient_class": "aroma_chemical", "chemical_class": "aldehyde", "odor_family": "aldehydic", "odor_description": "Sweet orange, waxy, fatty", "odor_strength": "very_strong", "odor_tenacity_hours": "68.0", "top_note": "yes", "heart_note": "yes", "base_note": "no", "blending_factor_1_10": "10.0", "threshold_of_detection_ppb": "10.0", "molecular_weight_Da": "156", "boili…

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (2)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Regulatory (2)
JECFA Number
104
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ALDEHYDE C-10 | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 40-JECFA 49/147 (1997)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Deodorizer Flavouring and nutrient Fragrance No specific technical function
Regulatory List Membership (4)
IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS) Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for Decanal.

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive jecfa_safe

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Decanal by CAS number or substance name.

Studies
8
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
300 mg/kg bw/day
ToxValDB_ECHA_IUCLID ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip

Known Synonyms

BRN 1362530 EINECS 203-957-4 FEMA No. 2362 UNII-31Z90Q7KQJ 1-Decanal 1-Decanal(mixed isomers) 1-decyl aldehyde Aldehyde c10 C-10 Aldehyde Decanal (ACD/Name 4.0) N-Decanal (capric aldehyde)

Chemical Function

Fragrance

Regulatory Lists

SCIL (9/2019) inert_ingredient; non_food_use; Pesticides air; detected; emissions; Europe; Toys and children's products air; Cleaning products and household care - laundry and fabric treatment; detected; emissions air; Cleaning products and household care - air freshener; detected; emissions Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; Europe air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe Cleaning products and household care - air freshener; Europe air; Cleaning products and household care - air freshener; detected; emissions; Europe air; detected; emissions; Europe; Toys and children's products air; detected; emissions; Europe; Toys and children's products air; detected; emissions; Europe; Toys and children's products air; Cons electronics mech appliances and machinery; detected; emissions; Europe Australia; Food and drug - smoking-related products IFRA Transparency Europe

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
DECANAL
ChEMBL ID
CHEMBL2228377
View full pharmaceutical profile →

Frequently Asked Questions

Is Decanal safe in cosmetics?

Decanal has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is Decanal allowed in the EU?

Decanal EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decanal do in cosmetics?

Decanal functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 112-31-2.

What is the NOAEL for Decanal?

The NOAEL (No Observed Adverse Effect Level) for Decanal is =200 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is Decanal used outside cosmetics?

Decanal also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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