NOAEL Studies Cosmetic Ingredient

Decanal NOAEL Studies

INCI: DECANAL

CAS: 112-31-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ECHA 12 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA LOAEL 1500 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=cffa889f-a93d-4952-a86c-17a08c603bb2
ECHA LOAEL 1500 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=cffa889f-a93d-4952-a86c-17a08c603bb2
ECHA LOAEL 1500 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=cffa889f-a93d-4952-a86c-17a08c603bb2
ECHA NOAEL 300 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=9f7781b5-d235-4c6f-bee5-85bb4d09cd46
ECHA NOAEL 200 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=organ weights and organ / body weight ratios; key_result=true; entry_uuid=1370fb0b-b239-4260-a35c-917957a8381b
ECHA NOAEL 300 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=9f7781b5-d235-4c6f-bee5-85bb4d09cd46
ECHA NOAEL 200 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=organ weights and organ / body weight ratios; key_result=true; entry_uuid=1370fb0b-b239-4260-a35c-917957a8381b
ECHA NOAEL 300 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=mortality; key_result=true; entry_uuid=9f7781b5-d235-4c6f-bee5-85bb4d09cd46
ECHA NOAEL 200 mg/kg bw/day rat oral: gavage - one-generation reproductive toxicity dossier=42781653-0df5-4bdf-899c-6b3f824e4318.i6z; document=aa3e557a-5409-4b66-a3fa-c305e26eee6a_42781653-0df5-4bdf-899c-6b3f824e4318.i6d; document_key=aa3e557a-5409-4b66-a3fa-c305e26eee6a/42781653-0df5-4bdf-899c-6b3f824e4318; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1990; ReportDate=1990-01-01; basis=organ weights and organ / body weight ratios; key_result=true; entry_uuid=1370fb0b-b239-4260-a35c-917957a8381b
ECHA LOAEL =1500 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa64e4b0a7c65d1b59f9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13619/7/9/2?documentUUID=42781653-0df5-4bdf-899c-6b3f824e4318; YEAR=1964; ORIGINAL_YEAR=1964; TOXICOLOGICAL_EFFECT=P0: clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855070_15855115_15855552_15855634_15855959_15855997_15856355_15856409:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_54c0a4514ff1425c41b88786be683527
ECHA NOAEL =300 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa64e4b0a7c65d1b59f9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13619/7/9/2?documentUUID=42781653-0df5-4bdf-899c-6b3f824e4318; YEAR=1964; ORIGINAL_YEAR=1964; TOXICOLOGICAL_EFFECT=P0: clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855070_15855115_15855552_15855634_15855959_15855997_15856355_15856409:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0f5e1232e18edd6df88fb7482facedd4
ECHA NOAEL =200 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa64e4b0a7c65d1b59fb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/13619/7/9/2?documentUUID=42781653-0df5-4bdf-899c-6b3f824e4318; YEAR=1964; ORIGINAL_YEAR=1964; TOXICOLOGICAL_EFFECT=F1: organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=organ weight; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15858936_15859002_15859564_15859656:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_724de2d548d7565af7b9045498a021b2
NTP ICE acute oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE acute oral LD50 =3730 mg/kg bw Rat oral acute Rat Acute Oral Toxicity NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_1176; row=7044; data_type=In Vivo; mixture=Chemical; chemical_name=Decanal; preferred_name=Decanal; dtxsid=DTXSID4021553; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID4021553; source_file=acute_oral.xlsx
NTP ICE endocrine 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP ICE endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=7416; RecordID=ARPathway2016_603; DatasetName=ARPathway2016; DTXSID=DTXSID4021553; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID4021553
ToxValDB GESTIS DNEL 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL local =62.14 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15630928_15630929:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_baa5f6fe74061251e01b05d7a3b95094
ToxValDB GESTIS DNEL DNEL systemic =24.86 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15630928_15630929:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_eca4dce949ae164812f0a1d454d1ce21
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 31Z90Q7KQJ UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"}
openFDA substances FDA UNII substance identifier 31Z90Q7KQJ UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"}
openFDA substances FDA UNII substance identifier 31Z90Q7KQJ UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"}
openFDA substances FDA UNII substance identifier 31Z90Q7KQJ UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H20O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"31Z90Q7KQJ"}