Good UV Filter / Sunscreen NOAEL Data SCCS/CIR Reviewed

Cyamopsis Tetragonoloba (Guar) Gum

Also known as: α-D-galacto-β-D-Mannan, α-D-Galactopyrano-β-D-mannopyranan, Burtonite V-7-E, EINECS 232-536-8, FEMA No. 2537 (+11 more)

INCI: CYAMOPSIS TETRAGONOLOBA (GUAR) GUM

Cyamopsis Tetragonoloba (Guar) Gum (CAS 9000-30-0) is a cosmetic uv filter / sunscreen functioning as Thickening agent, stabilizer. Reported NOAEL =1000 mg/kg body weight in rat (CIR_vision_codex); EU Regulation 1223/2009 status: restricted; 2 safety opinions reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 9000-30-0 →

Auto-generated CPSR Part A draft with source citations
Function
Thickening agent, stabilizer
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Generally recognized as safe for cosmetic use

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cyamopsis Tetragonoloba (Guar) Gum.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Cyamopsis Tetragonoloba (Guar) Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =2500 mg/kg bw/day - Rat chronic/long term toxicity EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
NOAEL =2500 mg/kg bw/day - Rat chronic/long term toxicity EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe
NOAEL: 1000 mg/kg body weight (oral)

netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio

cir
Verdict: safe
NOAEL: 1000 mg/kg body weight (not specified)

netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio

EPA ToxValDB — Toxicity Values

3 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 =8100 mg/kg Mouse oral - ChemIDplus
LD50 =7000 mg/kg Rabbit oral - ChemIDplus
LD50 =6770 mg/kg Rat oral - ChemIDplus

Additional Ingredient Properties

1 property record from structured ingredient metadata.

biopolymer
{"cas_number": "9000-30-0", "polymer_class": "seed_gum", "botanical_source": "Cyamopsis tetragonoloba (Guar bean)", "molecular_weight_range_kDa": "220-2000", "monosaccharide_composition": "mannose/galactose (1.8:1)", "degree_of_branching": "moderately_branched", "charge_type": "nonionic", "viscosity_1pct_solution_mPas": "3000-6000", "pseudoplastic_behavior": "strong", "thixotropy": "moderate", "yi…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-caking agent Antioxidant Binder Deodorizer Drier Emulsifier Film former Flavouring and nutrient Fragrance Humectant
Regulatory List Membership (3)
EU Regulated in Personal Care EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Cyamopsis Tetragonoloba (Guar) Gum.

Regulatory Flags

EU Restricted epa_safer_alternative fda_food_additive

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Cyamopsis Tetragonoloba (Guar) Gum by CAS number or substance name.

Studies
6
Lowest NOAEL
1000
Highest NOAEL
2500

Units vary across source rows: mg/kg bw/day, mg/kg body weight

EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx CIR_vision_codex

Known Synonyms

α-D-galacto-β-D-Mannan α-D-Galactopyrano-β-D-mannopyranan Burtonite V-7-E EINECS 232-536-8 FEMA No. 2537 Guar gum (Cyamopsis tetragonolobus (L.)) Jaguar A 20 B Jaguar gum A-20-D Jaguar No.124 Jaguar plus NCI-C50395 Supercol G.F. Cyamopsis tetragonoloba Guar Gum Seed Endosperm UNII-E89I1637KE Guar gum

Chemical Function

Regulatory Lists

active_ingredient; Pesticides inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides Europe; Personal care Europe; Personal care fracking SCIL (9/2019) Canada; pharmaceutical fracking; water food_additive; Substances Added to Food (formerly EAFUS) (2/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
302
View full pharmaceutical profile →

Frequently Asked Questions

Is Cyamopsis Tetragonoloba (Guar) Gum safe in cosmetics?

Cyamopsis Tetragonoloba (Guar) Gum has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 6 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is Cyamopsis Tetragonoloba (Guar) Gum allowed in the EU?

Cyamopsis Tetragonoloba (Guar) Gum EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cyamopsis Tetragonoloba (Guar) Gum do in cosmetics?

Cyamopsis Tetragonoloba (Guar) Gum functions as: Thickening agent, stabilizer. It is classified as a UV Filter / Sunscreen in our database. CAS number: 9000-30-0.

What is the NOAEL for Cyamopsis Tetragonoloba (Guar) Gum?

The NOAEL (No Observed Adverse Effect Level) for Cyamopsis Tetragonoloba (Guar) Gum is =1000 mg/kg body weight based on a developmental toxicity study via oral route in rat. A total of 6 study endpoints are available. Source: CIR_vision_codex.

Is Cyamopsis Tetragonoloba (Guar) Gum used outside cosmetics?

Cyamopsis Tetragonoloba (Guar) Gum also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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