Is Creatine safe in cosmetics?
Creatine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Creatine
INCI: CREATINE
Creatine (CAS None) is a cosmetic cosmetic ingredient functioning as high-energy phosphoryl group reservoir. EU Regulation 1223/2009 status: permitted, max 0.015%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS None →
Auto-generated CPSR Part A draft with source citations
Function
high-energy phosphoryl group reservoir
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.015%
US US Status
permitted
US Notes
CIR safety
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Creatine.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
6 property records from structured ingredient metadata.
acne
{"cas_number": "57-00-1", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_ac…
amino_acid
{"cas_number": "57-00-1", "ingredient_class": "amino_acid", "source_origin": "synthetic", "molecular_weight_range_Da": "131", "amino_acid_composition_key": "guanidine_derivative", "charge_at_pH_5_5": "cationic", "water_solubility": "soluble", "oil_solubility": "insoluble", "film_forming_ability": "poor", "moisture_binding_capacity": "moderate", "NMF_component": "no", "skin_penetration_depth": "epi…
anti_aging
{"anti_aging_claim": "anti-wrinkle, firming", "mechanism_of_action": "Specialized bioactive mechanism", "target_skin_layer": "epidermis, dermis", "collagen_stimulation": "Mild", "elastin_protection": "Moderate", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "12", "sample_size": "28", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Specialized research …
hair_care
{"hair_function": "strengthening", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "high", "protein_sensitivity": "protein", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "strengthens",…
hair_conditioning
{"cas_number": "57-00-1", "ingredient_class": "bond_repair", "chemical_type": "amino_acid", "substantivity_to_hair": "good", "deposition_from_shampoo": "yes", "deposition_from_conditioner": "yes", "conditioning_mechanism": "hydrogen_bond_restoration", "hair_penetration": "cuticle_cortex", "molecular_weight_effect_on_penetration": "small_molecule_penetrates", "wet_combing_force_reduction_pct": "10-…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
Expert Verdict
Expert safety assessment and concern-level summary for Creatine.
Regulatory Flags
eu_children_restricted
Frequently Asked Questions
Is Creatine allowed in the EU?
Creatine EU regulatory status: permitted. Maximum allowed concentration: 0.015%. This is based on EU Regulation 1223/2009 and its amendments.
What does Creatine do in cosmetics?
Creatine functions as: high-energy phosphoryl group reservoir. It is classified as a cosmetic ingredient in our database. CAS number: None.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Good
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(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
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