Is Cinchona Succirubra Bark Extract safe in cosmetics?
Cinchona Succirubra Bark Extract has a safety rating of "POOR" in our database. EU status: restricted. US status: permitted.
Poor
Cosmetic Ingredient
Cinchona Succirubra Bark Extract
INCI: CINCHONA SUCCIRUBRA BARK EXTRACT
Cinchona Succirubra Bark Extract (CAS 84776-28-3) is a cosmetic cosmetic ingredient functioning as Hair conditioning, skin conditioning. EU Regulation 1223/2009 status: restricted, max Rinse-off hair <=0.5%, leave-on hair <=0.2% (as free quinine base). Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 84776-28-3 →
Auto-generated CPSR Part A draft with source citations
Function
Hair conditioning, skin conditioning
Safety Rating
POOR
Regulatory Status
EU EU Status
restricted
EU Max Conc.
Rinse-off hair <=0.5%, leave-on hair <=0.2% (as free quinine base)
US US Status
permitted
US Notes
No FDA prohibition for cosmetic use. Quinine FDA-permitted in beverages only (<=83 ppm). No CIR monograph. Post-MoCRA safety substantiation required.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cinchona Succirubra Bark Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
anti_pollution
{"cas_number": "84776-28-3", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulati…
depigmentation
{"cas_number": "not established", "ingredient_class": "combined_mechanism", "primary_mechanism_of_action": "Tannins, flavonoids, and saponins provide brightening", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduction_pct_clinical": "15-30…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Cinchona Succirubra Bark Extract.
Regulatory Flags
EU_RESTRICTED
CONTROVERSIAL
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Cinchona Succirubra Bark Extract allowed in the EU?
Cinchona Succirubra Bark Extract EU regulatory status: restricted. Maximum allowed concentration: Rinse-off hair <=0.5%, leave-on hair <=0.2% (as free quinine base). This is based on EU Regulation 1223/2009 and its amendments.
What does Cinchona Succirubra Bark Extract do in cosmetics?
Cinchona Succirubra Bark Extract functions as: Hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84776-28-3.
Compliance Tools
Check Cinchona Succirubra Bark Extract compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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