Is CI 28440 safe in cosmetics?
CI 28440 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: prohibited. 3 toxicological study endpoint(s) are available in our database.
CI 28440
Also known as: C.I. Food Black 1, tetrasodium salt, Blue Black BN, Brilliant Acid Black BN Extra Pure A, Brilliant Acid Black BNA Export, Brilliant Black (+15 more)
CI 28440 (CAS 2519-30-4) is a cosmetic cosmetic ingredient functioning as Colorant. Reported NOAEL =1300 mg/kg bw/day in Mouse (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 2519-30-4 →
Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
tetrasodium;4-acetamido-5-hydroxy-6-[[7-sulfonato-4-[(4-sulfonatophenyl)diazenyl]naphthalen-1-yl]diazenyl]naphthalene-1,7-disulfonate
InChIKey
GMMAPXRGRVJYJY-UHFFFAOYSA-J
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Not listed as FDA-approved color additive for US cosmetics; banned in US and Japan for food use; no certification for cosmetic use in 21 CFR
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 28440.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for CI 28440. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1300 mg/kg bw/day | oral | Mouse | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =1500 mg/kg bw/day | oral | Rat | developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =2000 mg/kg bw/day | dermal | Rat | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Black
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (IV - Colorants)
BRIN Brazil/India Cosmetics
India: Permitted Colorant
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | permitted_colorant | - | All products |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for CI 28440.
Regulatory Flags
azo-dye
eu-annex-iv
not-fda-approved
us-banned-food
e151
brilliant-black-bn
water-soluble
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to CI 28440 by CAS number or substance name.
Studies
3
Lowest NOAEL
1300 mg/kg bw/day
Highest NOAEL
2000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
C.I. Food Black 1, tetrasodium salt
Blue Black BN
Brilliant Acid Black BN Extra Pure A
Brilliant Acid Black BNA Export
Brilliant Black
Brilliant Black A
Brilliant Black N. FQ
Brilliant Black BN
Brilliant Black NAF
Certicol Black PNW
Cilefa Black B
Edicol Supra Black BN
EINECS 219-746-5
Hexacol Black PN
Melan Black
L-Schwarz 1
Xylene Black F
Brilliantschwarz BN
CERN brilantni PN
CERN potravinarska 1
Chemical Function
Dye
Regulatory Lists
consumer_product; Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Brilliant Black BN / Black PN
E Number
E151
ADI
5 mg/kg bw
Food Category
colorant
Frequently Asked Questions
Is CI 28440 allowed in the EU?
CI 28440 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 28440 do in cosmetics?
CI 28440 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 2519-30-4.
What is the NOAEL for CI 28440?
The NOAEL (No Observed Adverse Effect Level) for CI 28440 is =1300 mg/kg bw/day based on a chronic study via oral route in Mouse. A total of 3 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is CI 28440 used outside cosmetics?
CI 28440 also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check CI 28440 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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