Is Ceratonia Siliqua Gum safe in cosmetics?
Ceratonia Siliqua Gum has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Ceratonia Siliqua Gum
Also known as: Carob bean extract (Ceratonia siliqua L.), Carob bean flour, EINECS 232-541-5, FEMA No. 2243, FEMA No. 2648 (+10 more)
INCI: CERATONIA SILIQUA GUM
Ceratonia Siliqua Gum (CAS 9000-40-2) is a cosmetic cosmetic ingredient functioning as rheology modifier, thickener, gelling agent, stabilizer. NOAEL 2500 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9000-40-2 →
Auto-generated CPSR Part A draft with source citations
Function
rheology modifier, thickener, gelling agent, stabilizer
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS for food; widely used in cosmetics. No restriction.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ceratonia Siliqua Gum.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Ceratonia Siliqua Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 910 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1300 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 15000 mg/kg bw/day | oral | mouse | Short Term Toxicity | COSMOS_DB |
| NOAEL | =1 mg/kg bw/day | oral | Rat | Subchronic toxicity | INCHEM_WHO_jecfa_jecmono_v1000je01 |
| NOAEL | =1 mg/kg bw/day | oral | Rat | Subchronic toxicity | INCHEM_WHO_jecfa_jecmono_v1000je01 |
| NOAEL | =8 mg/kg bw/day | - | Rat | Acute toxicity | INCHEM_WHO_jecfa_jecmono_v1000je01 |
| NOAEL | =8 mg/kg bw/day | - | Rat | Acute toxicity | INCHEM_WHO_jecfa_jecmono_v1000je01 |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ceratonia Siliqua Gum across SCCS product categories, with measured dermal absorption where available.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Binder
Deodorizer
Dye
Emulsifier
Film former
Flavouring and nutrient
Fragrance
Softener and conditioner
Solvent
Thickening agent
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Ceratonia Siliqua Gum.
Regulatory Flags
eu-compliant
biodegradable
reach-spm-exempt
natural-polymer
cosmos-eligible
ecocert
gras
xanthan-synergy
elastic-gel
hot-process-required
carbomer-alternative
ifra_fragrance
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Ceratonia Siliqua Gum by CAS number or substance name.
Studies
203
Lowest NOAEL
1 mg/kg bw/day
Highest NOAEL
15000 mg/kg bw/day
COSMOS_DB
INCHEM_WHO_jecfa_jecmono_v1000je01
INCHEM_WHO_jecfa_jecmono_v73je01
Known Synonyms
Carob bean extract (Ceratonia siliqua L.)
Carob bean flour
EINECS 232-541-5
FEMA No. 2243
FEMA No. 2648
Gum,carob bean
Gum,carob bean locust
Johannisbrotmehl
Locust bean flour
Locust bean gum (Ceratonia siliqua L.)
NCI-C50419
St. John's bread
St John's bread gum
Supercol
UNII-V4716MY704
Chemical Function
Softener and conditioner
Film former
Deodorizer
Viscosity modifier
Emulsifier
Binder
Flavouring and nutrient
Fragrance
Dye
Regulatory Lists
Australia; Food and drug - smoking-related products
consumer_product
IFRA Transparency
consumer_product
inert_ingredient; Pesticides
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Ceratonia Siliqua Gum allowed in the EU?
Ceratonia Siliqua Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ceratonia Siliqua Gum do in cosmetics?
Ceratonia Siliqua Gum functions as: rheology modifier, thickener, gelling agent, stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 9000-40-2.
What is the NOAEL for Ceratonia Siliqua Gum?
The NOAEL (No Observed Adverse Effect Level) for Ceratonia Siliqua Gum is 910 mg/kg bw/day based on a Developmental study via oral route in rabbit. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Ceratonia Siliqua Gum compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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