Excellent Cosmetic Ingredient NOAEL Data Dermal Penetration

Carbomer

Also known as: Acrylic acid, polymers, Acrylic acid homopolymer, Acrylic acid polymer, Acrylic acid resin, Poly(acrylic acid)-butyl acrylate-2-hydroxyethyl acrylate copolymer complex (+15 more)

INCI: CARBOMER

Carbomer (CAS 9003-01-4) is a cosmetic cosmetic ingredient functioning as Film-forming polymer; thickener; gelling agent; emulsion stabilizer. Reported NOAEL =53 mg/kg bw/day in Rat (ECHA); EU Regulation 1223/2009 status: restricted, max 0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 9003-01-4 →

Auto-generated CPSR Part A draft with source citations
Function
Film-forming polymer; thickener; gelling agent; emulsion stabilizer
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
618-347-7

Regulatory Status

EU EU Status restricted
EU Max Conc. 0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035
US US Status permitted
US Notes CIR: safe as used (reaffirmed 2003); most widely used acrylates copolymer with 6,434 formulations in VCRP 2018 data; modern grades specify benzene residual well below regulatory limits; no US restriction

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Carbomer.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Carbomer. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =53 mg/kg bw/day oral Rat reproduction developmental ECHA
NOAEL =240 mg/kg bw/day oral Rat reproduction developmental ECHA
NOAEL =460 mg/kg bw/day oral Rat reproduction developmental ECHA

Dermal Penetration Profile

Skin absorption and penetration characteristics of Carbomer, relevant to systemic exposure and MoS calculations.

Absorption %
0%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
no
Topical Bioavailability
0%
Safety Margin Factor
none

Source: CIR Expert Panel

IARC Carcinogenicity

International Agency for Research on Cancer (WHO) monograph evaluation.

IARC Group
3
Volume
19, Sup 7
Evaluation Year
1987

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Face Cream 0.1–0.5 2 CIR Safety Assessment
Serum 0.2–0.8 2 CIR Safety Assessment
Cleanser 0.1–0.5 1 CIR Safety Assessment
Sunscreen 0.1–0.5 1 CIR Safety Assessment

Additional Ingredient Properties

10 property records from structured ingredient metadata.

anti_pollution
{"cas_number": "9007-20-9", "ingredient_class": "anti_pollution", "primary_mechanism": "film_forming_barrier", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_…
baby_pediatric
{"cas_number": "9003-01-4/9007-20-9", "ingredient_class": "thickener_baby_safe", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Synthetic polymer, safe, non-irritating at proper pH", "transepidermal_absorption_risk_pediatric": "very_low", "dose_per_kg_body_weight_concern": "Non-absor…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "1", "skin_type_suitability": "all,oily,combination,normal,acne-prone", "acne_safe": "yes", "source": "Synthetic thickener"}
concentration
{"min_concentration_pct": "0.1", "max_concentration_pct": "1.0", "typical_concentration_pct": "0.5", "product_type": "Moisturizer", "function_at_concentration": "Thickener", "source": "CIR Safety Assessment"}
dermal_absorption
{"molecular_weight_da": "Variable", "skin_penetration_level": "surface", "penetration_depth": "surface only", "absorption_pct": "0", "systemic_absorption": "no", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0", "source": "CIR"}
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "non-biodegradable", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "physical harm from particles", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "yes", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted…
emulsifier
{"cas_number": "9003-01-4", "ingredient_class": "emulsion_stabilizer,polymeric_emulsifier", "chemical_type": "acrylic_copolymer", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.5-2", "surface_tension_reduction_mN_m": "28-35", "interfacial_tension_reduction": "32-38", "lamellar_phase": "no", "hexagonal_phase": "no", "cubic_phase": "no", "gel_network_formation": "no", "viscoelastic_pr…
hair_care
{"hair_function": "styling", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "keratin_b…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter Binder Biocide Chelating agent Corrosion inhibitor Defoamer Dispersing agent Emulsifier Film former Flow promoter
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL) FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for Carbomer.

Regulatory Flags

eu-microplastic-restriction reach-2023-2055 leave-on-ban-2029 rinse-off-ban-2027 colour-cosmetics-ban-2035 synthetic-polymer non-biodegradable electrolyte-sensitive reformulation-required echa-reporting derogation-5 eu_children_restricted epa_safer_alternative

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Carbomer by CAS number or substance name.

Studies
3
Lowest NOAEL
53 mg/kg bw/day
Highest NOAEL
460 mg/kg bw/day
ECHA

Known Synonyms

Acrylic acid, polymers Acrylic acid homopolymer Acrylic acid polymer Acrylic acid resin Poly(acrylic acid)-butyl acrylate-2-hydroxyethyl acrylate copolymer complex 2-Propenic acid homopolymer, Polyacrylic acid, Carboxypolymethylene Poly(acrylic acid) 2-Propenoic Acid, Polymer ACRYLIC ACID, OLIGOMERS POLYACRYLATE POLYACRYLIC ACID HOMOPOLYMER Alcosperse 409 Alcoprint PTF-Z 328 Aquatreat AR 4 Aqualic HL 415 Carboxypolymethylene Synocure 866EEP75 Three Bond 1131 Versicol E 15 Turfine P 20

Chemical Function

Dispersing agent Binder Thickening agent

Regulatory Lists

SCIL (9/2019) CEDI inert_ingredient; Pesticides Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - hair styling and care - shampoo-dandruff Europe; Personal care - liniment inert_ingredient; non_food_use; Pesticides Indirect additives food contact (10/2018) Journal of Veterinary Diagnostic Investigation

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Carbomer safe in cosmetics?

Carbomer has a safety rating of "EXCELLENT" in our database. EU status: restricted. US status: permitted. 3 toxicological study endpoint(s) are available in our database.

Is Carbomer allowed in the EU?

Carbomer EU regulatory status: restricted. Maximum allowed concentration: 0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035. This is based on EU Regulation 1223/2009 and its amendments.

What does Carbomer do in cosmetics?

Carbomer functions as: Film-forming polymer; thickener; gelling agent; emulsion stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 9003-01-4.

What is the NOAEL for Carbomer?

The NOAEL (No Observed Adverse Effect Level) for Carbomer is =53 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 3 study endpoints are available. Source: ECHA.

Is Carbomer used outside cosmetics?

Carbomer also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Carbomer have different safety status in cosmetics vs industrial chemicals?

Carbomer is classified GHS Danger (H315, H319, H335, H340, H350) in the chemicals database but is restricted in EU cosmetics at max 0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035.

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