What is the NOAEL for Polyacrylic acid?
Polyacrylic acid has 26 NOAEL studies in the database. The lowest reported value is 1.97 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
IARC Group 3
REACH Registered
Cosmetic Ingredient
Polyacrylic acid
Also known as: Acrylic acid, polymers, Acrylic acid homopolymer, Acrylic acid polymer, Acrylic acid resin, Poly(acrylic acid)-butyl acrylate-2-hydroxyethyl acrylate copolymer complex (+15 more)
CAS 9003-01-4
Polyacrylic acid (CAS 9003-01-4) is a chemical substance; key hazard signal: IARC Group 3. Key regulatory status: REACH registered, 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC, ECHA REACH.
Cross-Vertical Regulatory Divergence
Polyacrylic acid is classified GHS Danger (H315, H319, H335, H340, H350) in the chemicals database but is restricted in EU cosmetics at max 0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
26
SOURCE
chemical inventory jurisdictions
Regulatory lists
10
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Polyacrylic acid
CAS Number
9003-01-4
DTXSID
DTXSID50873988
Synonyms
Acrylic acid, polymersAcrylic acid homopolymerAcrylic acid polymerAcrylic acid resinPoly(acrylic acid)-butyl acrylate-2-hydroxyethyl acrylate copolymer complex2-Propenic acid homopolymer, Polyacrylic acid, CarboxypolymethylenePoly(acrylic acid)2-Propenoic Acid, PolymerACRYLIC ACID, OLIGOMERSPOLYACRYLATEPOLYACRYLIC ACID HOMOPOLYMERAlcosperse 409
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1987 | 19, Sup 7 |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Dispersing agentBinderThickening agentStabilizing agentFilm formerViscosity modifierEmulsifierpH regulating agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - hair styling and care - shampoo-dandruff | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care - liniment | Danish Environmental Protection Agency | Danish EPA |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| - | Journal of Veterinary Diagnostic Investigation | Published Articles |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 26 of 26 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1.97 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 73861X4K5F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 73861X4K5F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 73861X4K5F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 73861X4K5F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9G2MAD7J6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9G2MAD7J6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9G2MAD7J6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9G2MAD7J6W | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A8371R0U5J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A8371R0U5J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A8371R0U5J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A8371R0U5J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D0I6NSZ87U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D0I6NSZ87U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D0I6NSZ87U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D0I6NSZ87U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KD3S7H73D3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KD3S7H73D3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KD3S7H73D3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KD3S7H73D3 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP_ICE_cancer |
| =53 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =240 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =460 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 26 of 26 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-Propenoic acid, homopolymer | 618-347-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035
Category
thickener
Frequently Asked Questions
What regulatory lists include Polyacrylic acid?
Polyacrylic acid appears on 7 regulatory/inventory lists including SCIL (9/2019), CEDI, inert_ingredient; Pesticides, and 4 more. Source: EPA CPDat.
Is Polyacrylic acid a carcinogen according to IARC?
Polyacrylic acid is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is Polyacrylic acid used in cosmetics?
Yes, Polyacrylic acid is also indexed as a cosmetic ingredient under the name Carbomer. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polyacrylic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Polyacrylic acid have different safety status in cosmetics vs industrial chemicals?
Polyacrylic acid is classified GHS Danger (H315, H319, H335, H340, H350) in the chemicals database but is restricted in EU cosmetics at max 0.01% concentration threshold; rinse-off (non-scrub) ban from 17 Oct 2027; leave-on ban from 17 Oct 2029; colour cosmetics ban deferred to 17 Oct 2035.
Is Polyacrylic acid used outside industrial chemicals?
Polyacrylic acid also appears in cosmetics databases.