Is Butadiene safe in cosmetics?
Butadiene has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Butadiene
INCI: BUTADIENE
Butadiene (CAS 106-99-0) is a cosmetic cosmetic ingredient functioning as Industrial monomer; not intended for direct cosmetic use. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 106-99-0 →
Auto-generated CPSR Part A draft with source citations
Function
Industrial monomer; not intended for direct cosmetic use
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
buta-1,3-diene
InChIKey
KAKZBPTYRLMSJV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Prohibited substance; not applicable for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Butadiene.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Butadiene.
Regulatory Flags
prop65
eu_banned_cosmetics
eu_cosing_listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BUTADIENE
ChEMBL ID
CHEMBL537970
Frequently Asked Questions
Is Butadiene allowed in the EU?
Butadiene EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Butadiene do in cosmetics?
Butadiene functions as: Industrial monomer; not intended for direct cosmetic use. It is classified as a cosmetic ingredient in our database. CAS number: 106-99-0.
Is Butadiene used outside cosmetics?
Butadiene also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Butadiene compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Butadiene in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Butadiene in your formulation.