INCI: BIS(BUTYLBENZOATE) DIAMINOTRIAZINE AMINOPROPYLTRISILOXANE
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane (CAS 207562-42-3) is a cosmetic cosmetic ingredient functioning as UV absorber / UV filter. Reported NOAEL =1.34 mg/kg bw/day in rat (SCCS Opinion); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
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Margin of Safety, dermal absorption, and sensitization profile summaries for Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane.
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10 study endpoints found for Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1.34 mg/kg bw/day | oral | rat | NOAEL study | SCCS Opinion |
| NOAEL | =1.34 mg/kg bw/day | oral | rat | NOAEL study | SCCS Opinion |
| NOAEL | =1.34 mg/kg bw/day | oral | rat | NOAEL study | SCCS Opinion |
| NOAEL | =1.34 mg/kg bw/day | oral | rat | NOAEL study | SCCS Opinion |
| NOAEL | =1000 mg/kg bw/day | oral | rat | repeated dose toxicity | SCCS Opinion |
| NOAEL | =1000 mg/kg bw/d | oral | - | genotoxicity | SCCS Opinion |
| NOAEL | =1000 mg/kg bw/day | oral | rat | repeated dose toxicity | SCCS Opinion |
| NOAEL | =1000 mg/kg bw/d | oral | - | genotoxicity | SCCS Opinion |
| NOAEL | =1000 mg/kg bw/day | oral | rat | repeated dose toxicity | SCCS Opinion |
| NOAEL | =1000 mg/kg bw/d | oral | - | genotoxicity | SCCS Opinion |
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured | 10.0% | in_vitro | - | SCCS/0055 |
| measured | 8.57% | - | - | SCCS/0055 |
| measured | 75.44% | - | - | SCCS/0055 |
| measured | 81.65% | - | - | SCCS/0055 |
| measured | 10.78% | - | - | SCCS/0055 |
Expert safety assessment and concern-level summary for Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane.
Public NOAEL study rows linked to Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane by CAS number or substance name.
Units vary across source rows: mg/kg bw/day, mg/kg bw/d
| Absorption % | Method | Vehicle |
|---|---|---|
| 10.0% | in_vitro | - |
| 8.57% | - | - |
| 75.44% | - | - |
| 81.65% | - | - |
| 10.78% | - | - |
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane functions as: UV absorber / UV filter. It is classified as a cosmetic ingredient in our database. CAS number: 207562-42-3.
The NOAEL (No Observed Adverse Effect Level) for Bis(Butylbenzoate) Diaminotriazine Aminopropyltrisiloxane is =1.34 mg/kg bw/day based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS Opinion.
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