Is Bifidobacterium Longum safe in cosmetics?
Bifidobacterium Longum has a safety rating of "MODERATE" in our database. EU status: permitted. US status: restricted.
Moderate
Cosmetic Ingredient
Bifidobacterium Longum
INCI: BIFIDA FERMENT LYSATE
Bifidobacterium Longum (CAS 96507-89-0) is a cosmetic cosmetic ingredient functioning as Ferment / Probiotic ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 96507-89-0 →
Auto-generated CPSR Part A draft with source citations
Function
Ferment / Probiotic ingredient
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR report. If building GMP-ready documentation, flag this ingredient as requiring a safety assessor justification or read-across strategy.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bifidobacterium Longum.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
10 property records from structured ingredient metadata.
acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "…
anti_aging
{"anti_aging_claim": "barrier-repair, anti-wrinkle", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytothera…
anti_pollution
{"cas_number": "96507-89-0", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement/microbiome", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF…
baby_pediatric
{"cas_number": "CAS-FUNC-43", "ingredient_class": "other", "pediatric_safety_rating": "good", "minimum_age_months": "3", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Probiotic/postbiotic - emerging baby care", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_conc…
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "150", "estimated_cost_per_kg_usd_high": "280", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Korea/Japan", "bulk_discount_threshold_kg": "5", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Saccharo…
deodorant
{"cas_number": "96507-89-0", "ingredient_class": "postbiotic_deodorant", "mechanism_of_action": "microbiome_modulation", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "45-65", "bacteriostatic": "no", "bactericidal": "no", "target_bacteria": "promotes beneficial", "microbiome_impact": "prebiotic", "axillary_microbiome_effect": "varies…
depigmentation
{"cas_number": "formulation", "ingredient_class": "keratinocyte_turnover_enhancer", "primary_mechanism_of_action": "Fermentation metabolites provide gentle brightening and barrier support", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduc…
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "14-28", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "palm_…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Bifidobacterium Longum.
Chemical Function
Softener and conditioner
Regulatory Lists
Canada
Personal care
Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Bifidobacterium Longum allowed in the EU?
Bifidobacterium Longum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bifidobacterium Longum do in cosmetics?
Bifidobacterium Longum functions as: Ferment / Probiotic ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 96507-89-0.
Compliance Tools
Check Bifidobacterium Longum compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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