Is Amyl Butyrate safe in cosmetics?
Amyl Butyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Amyl Butyrate
Also known as: Butanoic acid, pentyl ester, Pentyl butyrate, Amyl butanoate, BRN 1752307, EINECS 208-739-2 (+8 more)
INCI: AMYL BUTYRATE
Amyl Butyrate (CAS 540-18-1) is a cosmetic cosmetic ingredient functioning as Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 540-18-1 →
Auto-generated CPSR Part A draft with source citations
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; no FDA restriction; FEMA GRAS for flavor use; falls under fragrance exemption
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Amyl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Amyl Butyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Butanoic acid, pentyl ester
Pentyl butyrate
Amyl butanoate
BRN 1752307
EINECS 208-739-2
FEMA No. 2059
NSC 7935
Pentyl butanoate
n-Pentyl butanoate
n-Pentyl butyrate
n-Pentyl n-butyrate
1-Pentyl butyrate
UNII-3Q2JP0VD8J
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183048
Frequently Asked Questions
Is Amyl Butyrate allowed in the EU?
Amyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Amyl Butyrate do in cosmetics?
Amyl Butyrate functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 540-18-1.
Is Amyl Butyrate used outside cosmetics?
Amyl Butyrate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Amyl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Good
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