What is the NOAEL for N-Amyl butyrate?
N-Amyl butyrate has 5 NOAEL studies in the database. The lowest reported value is 3Q2JP0VD8J UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
N-Amyl butyrate
Also known as: Amyl butyrate, Butanoic acid, pentyl ester, Pentyl butyrate, Amyl butanoate, BRN 1752307 (+9 more)
CAS 540-18-1
N-Amyl butyrate (CAS 540-18-1) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
N-Amyl butyrate
CAS Number
540-18-1
DTXSID
DTXSID4041604
Molecular Formula
C9H18O2
InChI Key
CFNJLPHOBMVMNS-UHFFFAOYSA-N
Monoisotopic Mass
158.13068
Synonyms
Amyl butyrateButanoic acid, pentyl esterPentyl butyrateAmyl butanoateBRN 1752307EINECS 208-739-2FEMA No. 2059NSC 7935Pentyl butanoaten-Pentyl butanoaten-Pentyl butyraten-Pentyl n-butyrate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
20 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 3Q2JP0VD8J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3Q2JP0VD8J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3Q2JP0VD8J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| 1000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3183048
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include N-Amyl butyrate?
N-Amyl butyrate appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 2 more. Source: EPA CPDat.
Is N-Amyl butyrate used in cosmetics?
Yes, N-Amyl butyrate is also indexed as a cosmetic ingredient under the name Amyl Butyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for N-Amyl butyrate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is N-Amyl butyrate used outside industrial chemicals?
N-Amyl butyrate also appears in cosmetics, pharmaceutical, cannabis databases.