Is Ambrein safe in cosmetics?
Ambrein has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Ambrein
Ambrein (CAS 473-03-0) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 473-03-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(1R,2R,4aS,8aS)-1-[(E)-6-[(1S)-2,2-dimethyl-6-methylidenecyclohexyl]-4-methylhex-3-enyl]-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol
InChIKey
BIADSXOKHZFLSN-RMCJHQKMSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ambrein.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Expert Verdict
Expert safety assessment and concern-level summary for Ambrein.
Regulatory Flags
fragrance-component
natural-origin
Chemical Function
Fragrance
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
AMBREIN
ChEMBL ID
CHEMBL376021
Frequently Asked Questions
Is Ambrein allowed in the EU?
Ambrein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ambrein do in cosmetics?
Ambrein functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 473-03-0.
Is Ambrein used outside cosmetics?
Ambrein also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ambrein compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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