Is 3-Methyl-Gamma-Octalactone safe in cosmetics?
3-Methyl-Gamma-Octalactone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
3-Methyl-Gamma-Octalactone
INCI: 3-METHYL-GAMMA-OCTALACTONE
3-Methyl-Gamma-Octalactone (CAS 39212-23-2) is a cosmetic cosmetic ingredient functioning as Fragrance (parfuming) — declared as PARFUM on labels. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 39212-23-2 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (parfuming) — declared as PARFUM on labels
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
5-butyl-4-methyloxolan-2-one
InChIKey
WNVCMFHPRIBNCW-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically restricted by FDA for cosmetics; also GRAS for flavoring. RIFM safety assessment supports safe use at declared levels
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3-Methyl-Gamma-Octalactone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
WHISKEY LACTONE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/42 | FAS 40-JECFA 49/231
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for 3-Methyl-Gamma-Octalactone.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 3-Methyl-Gamma-Octalactone allowed in the EU?
3-Methyl-Gamma-Octalactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 3-Methyl-Gamma-Octalactone do in cosmetics?
3-Methyl-Gamma-Octalactone functions as: Fragrance (parfuming) — declared as PARFUM on labels. It is classified as a cosmetic ingredient in our database. CAS number: 39212-23-2.
Is 3-Methyl-Gamma-Octalactone used outside cosmetics?
3-Methyl-Gamma-Octalactone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 3-Methyl-Gamma-Octalactone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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