What is the NOAEL for Heparin?
Heparin has 55 NOAEL studies in the database. The lowest reported value is 1K5KDI46KZ UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Heparin
Also known as: Semuloparin, Tinzaparin, α-Heparin, Vitrum AB, Dalteparin (+4 more)
CAS 9005-49-6
Heparin (CAS 9005-49-6) is a chemical substance. Key regulatory status: 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
55
SOURCE
chemical inventory jurisdictions
Regulatory lists
9
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Heparin
CAS Number
9005-49-6
DTXSID
DTXSID20872761
Synonyms
SemuloparinTinzaparinα-HeparinVitrum ABDalteparinHeparin sulfateEC No.: 232-681-7EINECS 232-681-7232-681-7
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
9 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | US International Trade Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 55 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1K5KDI46KZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1K5KDI46KZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1K5KDI46KZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1K5KDI46KZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4QW4AN84NQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4QW4AN84NQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4QW4AN84NQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4QW4AN84NQ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5R0L1D739E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5R0L1D739E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5R0L1D739E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5R0L1D739E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7UQ7X4Y489 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7UQ7X4Y489 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7UQ7X4Y489 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7UQ7X4Y489 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9816XA9004 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9816XA9004 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9816XA9004 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9816XA9004 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E47C0NF7LV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E47C0NF7LV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E47C0NF7LV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E47C0NF7LV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M316WT19D8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M316WT19D8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M316WT19D8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M316WT19D8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P776JQ4R2F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P776JQ4R2F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P776JQ4R2F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| P776JQ4R2F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79O08V79F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79O08V79F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79O08V79F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S79O08V79F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T2410KM04A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T2410KM04A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T2410KM04A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T2410KM04A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V72OT3K19I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V72OT3K19I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V72OT3K19I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| V72OT3K19I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VL0L558GCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VL0L558GCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VL0L558GCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VL0L558GCB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =3 | mg/kg bw/day | NOAEL | subcutaneous | dog (Beagle; male/female) | FDA_Toxicity_d87e80d0-be6e-4688-8dd8-c85780d7157d_dossier.i6z |
| =5 | mg/kg bw/day | NOAEL | intravenous | monkey (other:; male/female) | FDA_Toxicity_d87e80d0-be6e-4688-8dd8-c85780d7157d_dossier.i6z |
Showing 50 of 55 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
heparin
ChEMBL Phase
Not listed
Adverse Events
5228
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Heparin?
Heparin appears on 3 regulatory/inventory lists including Canada; pharmaceutical, Canada; consumer_product; Substances in Products - Canada (4/2014), pharmaceutical. Source: EPA CPDat.
Is Heparin used in cosmetics?
Yes, Heparin is also indexed as a cosmetic ingredient under the name Heparin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Heparin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Heparin used outside industrial chemicals?
Heparin also appears in cosmetics, pharmaceutical databases.