What is the NOAEL for Triacylglycerol lipase?
Triacylglycerol lipase has 27 NOAEL studies in the database. The lowest reported value is 8224ZTC4MA UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Triacylglycerol lipase
Also known as: Lipase, triacylglycerol, EINECS 232-619-9, GA 56, Rizolipasa, Rizolipasum (+2 more)
CAS 9001-62-1
Triacylglycerol lipase (CAS 9001-62-1) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Triacylglycerol lipase is classified GHS Danger (H334) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
27
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Triacylglycerol lipase
CAS Number
9001-62-1
DTXSID
DTXSID0047458
Synonyms
Lipase, triacylglycerolEINECS 232-619-9GA 56RizolipasaRizolipasumUNII-8MYC33932OPancrelipase lipase
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
17 records
Cleaning agentChemical reaction regulatorSoftener and conditionerProcessing aids not otherwise specifiedFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| pharmaceutical | US International Trade Commission | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 27 of 27 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 8224ZTC4MA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8224ZTC4MA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8224ZTC4MA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8224ZTC4MA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MYC33932O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MYC33932O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MYC33932O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MYC33932O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCG8G5QG5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCG8G5QG5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCG8G5QG5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OCG8G5QG5K | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
| =20 | mL/kg bw | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >2740 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 569 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =669 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_WHO_JECFA_Tox_Studies |
| 1000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| >=1248.3 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 2000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 3535 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 4490 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 18181 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 27 of 27 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Lipase, triacylglycerol | 232-619-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Enzyme
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ChEMBL Phase
Not listed
Adverse Events
8
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Triacylglycerol lipase?
Triacylglycerol lipase appears on 5 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Canada; pharmaceutical, and 2 more. Source: EPA CPDat.
Is Triacylglycerol lipase used in cosmetics?
Yes, Triacylglycerol lipase is also indexed as a cosmetic ingredient under the name Lipase. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Triacylglycerol lipase come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Does Triacylglycerol lipase have different safety status in cosmetics vs industrial chemicals?
Triacylglycerol lipase is classified GHS Danger (H334) in the chemicals database but is allowed in EU cosmetics.
Is Triacylglycerol lipase used outside industrial chemicals?
Triacylglycerol lipase also appears in cosmetics, pharmaceutical, food safety databases.