Food Safety Substance
Triacylglycerol lipase
Triacylglycerol lipase is a food additive with no EU additive status row found in the EU, FDA has no questions in the US, and data from 5 regulatory sources.
Substance Identity
Resolved identifiers used to render this food-safety record.
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 631 | Triacylglycerol lipase from Fusarium oxysporum produced in Trichoderma reesei | FDA has no questions | For use in the production of baked goods not to exceed 10 mg TOS/kg | Scientific procedures | AB Enzymes GmbH |
| United States | 708 | Triacylglycerol lipase from Rhizopus oryzae produced in Aspergillus niger | At the notifier's request, FDA ceased to evaluate this notice | For use in the production of cocoa butter substitutes at a rate of 0.3-1 kg of lipase (and carrier) per ton of lipid. | Scientific procedures | Advanced Enzyme Technologies Ltd. |
| United States | 783 | Triacylglycerol lipase from Rhizopus oryzae produced in Aspergillus niger | FDA has no questions | For use in the in the production of cocoa butter substitutes and human milk fat substitutes at a maximum level of 1 kg of lipase enzyme preparation per ton of fat raw material. | Scientific procedures | Advanced Enzyme Technologies Ltd |
| United States | 1150 | Triacylglycerol lipase enzyme preparation produced by Trichoderma reesei expressing a gene for triacylglycerol lipase from Thermomyces lanuginosis | At the notifier's request, FDA ceased to evaluate this notice | Intended for use as an enzyme at up to 4 mg Total Organic Solids/kg cereal in the production of baked goods and other cereal based products. | Scientific procedures | AB Enzymes Inc. |
| United States | 1154 | Triacylglycerol lipase enzyme preparation produced by Komagataella phaffii expressing the gene encoding lipase from Fusarium oxysporum | FDA has no questions | Intended for use as an enzyme at up to 8.46 mg total organic solids (TOS)/kg flour in baking. | Scientific procedures | Lallemand Inc. |
| United States | 1161 | Triacylglycerol lipase enzyme preparation produced by Candida cylindracea | FDA has no questions | Intended for use as an enzyme at up to 1500 mg Total Organic Solids/kg raw material in the manufacture of cheeses and edible oils, as well as in various brewing, flavoring, and... | Scientific procedures | Meito Sangyo Co., Ltd. |
| United States | 1196 | Triacylglycerol lipase enzyme preparation produced by Trichoderma reesei expressing a gene encoding an engineered triacylglycerol lipase from Thermomyces lanuginosus | FDA has no questions | Intended for use as an enzyme at up to 4 mg Total Organic Solids (TOS)/kg flour in the production of baked goods and other cereal based products. | Scientific procedures | AB Enzymes Inc. |
| United States | 631 | Triacylglycerol lipase from <i>Fusarium oxysporum</i> produced in <i>Trichoderma reesei</i> | FDA has no questions | For use in the production of baked goods not to exceed 10 mg TOS/kg | Scientific procedures | AB Enzymes GmbH |
| United States | 708 | Triacylglycerol lipase from <I>Rhizopus oryzae</I> produced in <I>Aspergillus niger</I> | At the notifier's request, FDA ceased to evaluate this notice (in PDF) | For use in the production of cocoa butter substitutes at a rate of 0.3-1 kg of lipase (and carrier) per ton of lipid. | Scientific procedures | Advanced Enzyme Technologies Ltd. |
| United States | 783 | <I>Triacylglycerol lipase</I> from <I>Rhizopus oryzae</I> produced in <I>Aspergillus niger | FDA has no questions (in PDF) | For use in the in the production of cocoa butter substitutes and human milk fat substitutes at a maximum level of 1 kg of lipase enzyme preparation per ton of fat raw material. | Scientific procedures | Advanced Enzyme Technologies Ltd |
| United States | 1150 | Triacylglycerol lipase enzyme preparation produced by <i>Trichoderma reesei</i> expressing a gene for triacylglycerol lipase from <i>Thermomyces lanuginosis</i> | At the notifier's request, FDA ceased to evaluate this notice (in PDF) | Intended for use as an enzyme at up to 4 mg Total Organic Solids/kg cereal in the production of baked goods and other cereal based products. | Scientific procedures | AB Enzymes Inc. |
| United States | 1154 | Triacylglycerol lipase enzyme preparation produced by <i>Komagataella phaffii</i> expressing the gene encoding lipase from <i>Fusarium oxysporum</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 8.46 mg total organic solids (TOS)/kg flour in baking. | Scientific procedures | Lallemand Inc. |
| United States | 1161 | Triacylglycerol lipase enzyme preparation produced by <i>Candida cylindracea</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 1500 mg Total Organic Solids/kg raw material in the manufacture of cheeses and edible oils, as well as in various brewing, flavoring, and... | Scientific procedures | Meito Sangyo Co., Ltd. |
| United States | 1196 | Triacylglycerol lipase enzyme preparation produced by <i>Trichoderma reesei</i> expressing a gene encoding an engineered triacylglycerol lipase from <i>Thermomyces lanuginosus</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 4 mg Total Organic Solids (TOS)/kg flour in the production of baked goods and other cereal based products. | Scientific procedures | AB Enzymes Inc. |
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | LIPASE from ASPERGILLUS ORYZAE, VAR. | - | 9001-62-1 | NOT SPECIFIED | - | ENZYME_PREPARATION | 1974 |
| JECFA | LIPASE, animal | - | 9001-62-1 | NOT LIMITED | - | ENZYME_PREPARATION | 1971 |
| JECFA | LIPASE from FUSARIUM HETEROSPORUM expressed in OGATAEA POLYMORPHA | - | 9001-62-1 | NOT SPECIFIED | - | ENZYME_PREPARATION | 2015 |
| JECFA | LIPASE from THERMOMYCES LANUGINOSUS and FUSARIUM OXYSPORUM expressed in ASPERGILLUS ORYZAE | JECFA95-7 | 9001-62-1 | NOT SPECIFIED | - | ENZYME_PREPARATION | 2022 |
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Triacylglycerol lipase used for in food?
Triacylglycerol lipase appears in food-use rows as: ENZYME, FLAVORING AGENT OR ADJUVANT, PROCESSING AID.
Is Triacylglycerol lipase safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: JECFA ADI NOT SPECIFIED. US/FDA evidence: FDA has no questions.
What is the ADI for Triacylglycerol lipase?
Triacylglycerol lipase has this ADI/reference value in the food-safety tables: JECFA ADI NOT SPECIFIED. Source: JECFA 1974.
Is Triacylglycerol lipase also used in cosmetics?
Triacylglycerol lipase has a same-CAS cosmetics cross-reference: Lipase, EU status permitted.