What is the NOAEL for Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-?
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- has 5 NOAEL studies in the database. The lowest reported value is 900T44YNC7 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-
CAS 5422-34-4
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- (CAS 5422-34-4) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-
CAS Number
5422-34-4
DTXSID
DTXSID20863533
Molecular Formula
C5H11NO3
InChI Key
RZCHTMXTKQHYDT-UHFFFAOYSA-N
Monoisotopic Mass
133.073893
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
14 records
HumectantAnti-static agentSoftener and conditionerThickening agentSurfactant (surface active agent)FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 900T44YNC7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 900T44YNC7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 900T44YNC7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 900T44YNC7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >=900 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | N-2-hydroxyethyllactamide | 226-546-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Surfactant
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-?
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- appears on 4 regulatory/inventory lists including pharmaceutical, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- used in cosmetics?
Yes, Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- is also indexed as a cosmetic ingredient under the name Lactamide DEA. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- used outside industrial chemicals?
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- also appears in cosmetics, cannabis databases.