NOAEL Data REACH Registered Cosmetic Ingredient

Ethyl valerate

Also known as: EINECS 208-726-1, Ethyl valerianate, FEMA No. 2462, UNII-95R258T4P6, FEMA 2462 (+2 more)

CAS 539-82-2

Ethyl valerate (CAS 539-82-2) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Ethyl Valerate →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
Ethyl valerate
CAS Number
539-82-2
DTXSID
DTXSID6040161
Molecular Formula
C7H14O2
InChI Key
ICMAFTSLXCXHRK-UHFFFAOYSA-N
Monoisotopic Mass
130.09938
Synonyms
EINECS 208-726-1Ethyl valerianateFEMA No. 2462UNII-95R258T4P6FEMA 2462N-Valeric acid ethyl esterValeric acid, ethyl ester (8CI)

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 6 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
EuropeEuropean CommissionFl@vis
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
95R258T4P6UNIIFDA UNII substance identifier--openFDA substances
95R258T4P6UNIIFDA UNII substance identifier--openFDA substances
95R258T4P6UNIIFDA UNII substance identifier--openFDA substances
95R258T4P6UNIIFDA UNII substance identifier--openFDA substances
=120mg/kg bw/dayNOAELoral: drinking waterRatEFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx
=120mg/kg bw/dayNOAELoral: drinking waterRatEFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredEthyl valerate208-726-1ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL47483
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Ethyl valerate?

Ethyl valerate has 6 NOAEL studies in the database. The lowest reported value is 95R258T4P6 UNII. Source: openFDA substances.

What regulatory lists include Ethyl valerate?

Ethyl valerate appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is Ethyl valerate used in cosmetics?

Yes, Ethyl valerate is also indexed as a cosmetic ingredient under the name Ethyl Valerate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ethyl valerate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Ethyl valerate used outside industrial chemicals?

Ethyl valerate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.