NOAEL Data REACH Registered Cosmetic Ingredient

L-Rhamnose

Also known as: Isodulcit, Isodulcitol, L-Mannomethylose, Locaose, MANNOSE (L), 6-DEOXY- (+12 more)

CAS 3615-41-6

L-Rhamnose (CAS 3615-41-6) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Rhamnose →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 23 fields
Name
L-Rhamnose
CAS Number
3615-41-6
DTXSID
DTXSID7042647
Molecular Formula
C6H12O5
InChI Key
PNNNRSAQSRJVSB-BXKVDMCESA-N
Monoisotopic Mass
164.068473
Synonyms
IsodulcitIsodulcitolL-MannomethyloseLocaoseMANNOSE (L), 6-DEOXY-NSC 2056RHAMNOSERhamnose, L-L-(+)-RhamnoseEC No.: 222-793-4EINECS 222-793-4FEMA No. 3730

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
HumectantDeodorizerFlavouring and nutrientFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
Canada; pharmaceuticalDrugBankDrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
QN34XC755AUNIIFDA UNII substance identifier--openFDA substances
QN34XC755AUNIIFDA UNII substance identifier--openFDA substances
QN34XC755AUNIIFDA UNII substance identifier--openFDA substances
QN34XC755AUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered6-deoxy-L-mannose222-793-4ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for L-Rhamnose?

L-Rhamnose has 4 NOAEL studies in the database. The lowest reported value is QN34XC755A UNII. Source: openFDA substances.

What regulatory lists include L-Rhamnose?

L-Rhamnose appears on 2 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Canada; pharmaceutical. Source: EPA CPDat.

Is L-Rhamnose used in cosmetics?

Yes, L-Rhamnose is also indexed as a cosmetic ingredient under the name Rhamnose. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for L-Rhamnose come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is L-Rhamnose used outside industrial chemicals?

L-Rhamnose also appears in cosmetics, food safety databases.