2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol — EFSA toxicology reference values

Substance Identity

Analyte identity and classification used for this cannabis substance page.

SOURCE efsa substances

Analyte name

2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol

CAS number

128-50-7

Contaminant class

Cannabis Analyte

Contaminant Class Badge

Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.

SOURCE State Cannabis Regulations

Cannabis Analyte Cannabis contaminant class used to group state testing rows.

Dataset Snapshot

Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.

SOURCE cannabis page data

Quality score

2

thin

Jurisdictions

0

No state rows

Lab/analyte rows

0

0 failed (-)

Potency samples

0

128-50-7

EFSA Substance Identity

EFSA substance identity rows matched by chemical name or CAS.

SOURCE efsa openfoodtox 3 0 export repository

2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol

CAS 128-50-7 / mono-constituent substance

C11H18O / 5 dossier(s)

EFSA Reference Values

Reference values from efsa_reference_values_v2 for toxicology and food-safety context.

SOURCE efsa openfoodtox 3 0 export repository

Descriptor	Value	Population	Endpoint	Body
TTC Cramer Class I	30 µg/kg bw/day	consumers	-	-
TTC Cramer Class I	30 µg/kg bw/day	consumers	-	-
TTC Cramer Class I	30 µg/kg bw/day	consumers	-	-
TTC Cramer Class I	30 µg/kg bw/day	consumers	-	-
TTC Cramer Class I	30 µg/kg bw/day	consumers	-	-

EFSA Study Results

Endpoint-level study rows from efsa_study_results matched to this substance.

SOURCE efsa openfoodtox 3 0 export repository

Endpoint	Species	Route	Effect	Assessment
Carcinogenicity_EU_PPP	-	-	-	Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. In the previous version of Flavouring Group Evaluation 73 (FGE.73), EFSA considered 16 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA at their 59th meeting. This revision is made due to consideration of two additional substances, santalyl acetate [FL-no: 09.034] and santalyl phenylacetate [FL-no: 09.712], compared to the previous version of FGE.73 (FGE.73Rev1). These substances have been evaluated in FGE.207 due to structural concern for genotoxicity, and have been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 18 alicyclic primary alcohols, aldehydes, acids and related esters and one phenethyl alcohol evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of 10 primary saturated or unsaturated alicyclic alcohols, aldehydes and esters evaluated in the Flavouring Group Evaluation 12, Revision 3 (FGE.12Rev3).
Carcinogenicity_EU_PPP	-	-	-	The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 15 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of four primary saturated or unsaturated alicyclic alcohol, aldehyde, and esters evaluated in the Flavouring Group Evaluation 12 (FGE.12). The Panel concluded that the 15 substances in the JECFA flavouring group are structurally related to the group of four primary saturated or unsaturated alicyclic alcohol, aldehyde, and esters evaluated by EFSA in FGE.12.
Carcinogenicity_EU_PPP	-	-	-	Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. This revision is made due to consideration of one additional substance, beta-ionyl acetate [FL-no: 09.305], compared to the previous version of FGE.73 (FGE.73Rev2). This substance has been evaluated in FGE.213Rev1 due to structural concern for genotoxicity, and has been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 18 alicyclic alcohols, aldehydes, acids and related esters and one phenethyl alcohol evaluated by the JECFA (59th and 63rd meeting).
Carcinogenicity_EU_PPP	-	-	-	The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present FGE.96 concerns 88 JECFA-evaluated substances from different groups. These groups have been previously considered by EFSA in FGE.51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87. Common for all the 88 substances was that for none of them European production volumes were available at the time for the first consideration in the abovementioned FGEs. As a consequence, no MSDI could be calculated for EU and accordingly the substances could not be considered by EFSA using the Procedure.
Carcinogenicity_EU_PPP	-	-	-	The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The revision is made due to consideration of one additional substance, 2,6,6-trimethylcyclohexa-1,3-diene-1-carbaldehyde [FL-no: 05.104], compared to the previous version of FGE.73. This substance has been evaluated in FGE.209 due to structural concern for genotoxicity, and has been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 16 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of nine primary saturated or unsaturated alicyclic alcohol, aldehyde and esters evaluated in the Flavouring Group Evaluation 12, Revision 2 (FGE.12Rev2).
Genetic Toxicity	-	-	-	Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. This revision is made due to consideration of one additional substance, beta-ionyl acetate [FL-no: 09.305], compared to the previous version of FGE.73 (FGE.73Rev2). This substance has been evaluated in FGE.213Rev1 due to structural concern for genotoxicity, and has been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 18 alicyclic alcohols, aldehydes, acids and related esters and one phenethyl alcohol evaluated by the JECFA (59th and 63rd meeting).
Genetic Toxicity	-	-	-	Following a request from the European Commission, the EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was asked to deliver a scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the CEF Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. In the previous version of Flavouring Group Evaluation 73 (FGE.73), EFSA considered 16 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA at their 59th meeting. This revision is made due to consideration of two additional substances, santalyl acetate [FL-no: 09.034] and santalyl phenylacetate [FL-no: 09.712], compared to the previous version of FGE.73 (FGE.73Rev1). These substances have been evaluated in FGE.207 due to structural concern for genotoxicity, and have been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 18 alicyclic primary alcohols, aldehydes, acids and related esters and one phenethyl alcohol evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of 10 primary saturated or unsaturated alicyclic alcohols, aldehydes and esters evaluated in the Flavouring Group Evaluation 12, Revision 3 (FGE.12Rev3).
Genetic Toxicity	-	-	-	The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present FGE.96 concerns 88 JECFA-evaluated substances from different groups. These groups have been previously considered by EFSA in FGE.51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87. Common for all the 88 substances was that for none of them European production volumes were available at the time for the first consideration in the abovementioned FGEs. As a consequence, no MSDI could be calculated for EU and accordingly the substances could not be considered by EFSA using the Procedure.
Genetic Toxicity	-	-	-	The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns 15 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of four primary saturated or unsaturated alicyclic alcohol, aldehyde, and esters evaluated in the Flavouring Group Evaluation 12 (FGE.12). The Panel concluded that the 15 substances in the JECFA flavouring group are structurally related to the group of four primary saturated or unsaturated alicyclic alcohol, aldehyde, and esters evaluated by EFSA in FGE.12.
Genetic Toxicity	-	-	-	The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The revision is made due to consideration of one additional substance, 2,6,6-trimethylcyclohexa-1,3-diene-1-carbaldehyde [FL-no: 05.104], compared to the previous version of FGE.73. This substance has been evaluated in FGE.209 due to structural concern for genotoxicity, and has been cleared from this concern and thus may be evaluated through the Procedure. The present consideration therefore concerns 16 alicyclic primary alcohols, aldehydes, acids and related esters evaluated by the JECFA (59th meeting) and will be considered in relation to the European Food Safety Authority (EFSA) evaluation of nine primary saturated or unsaturated alicyclic alcohol, aldehyde and esters evaluated in the Flavouring Group Evaluation 12, Revision 2 (FGE.12Rev2).

Cross-Reference to Chemicals / Cosmetics / Food

Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.

SOURCE core public cross-reference

Cosmetics Nopol / permitted → Food / EFSA 15 EFSA rows on this page →

Frequently Asked Questions

FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.

SOURCE page FAQ dataset

What is the regulatory limit for 2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol in cannabis?

2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.

Which states test for 2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol?

2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol does not have state-level cannabis testing rows in the fetched page data.

What are the EFSA reference values for 2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol?

2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol has 5 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class I.

Is 2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol also regulated in cosmetics or food?

2-(6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethan-1-ol has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.