EFSA toxicology reference values
2,4-Dimethylpyridine
SOURCE
efsa openfoodtox 3 0 export repository
2,4-Dimethylpyridine (CAS 108-47-4). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
2,4-Dimethylpyridine is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 108-47-4
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
efsa substances
Analyte name
2,4-Dimethylpyridine
CAS number
108-47-4
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
108-47-4
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
efsa openfoodtox 3 0 export repository
2,4-Dimethylpyridine
CAS 108-47-4 / mono-constituent substance
C7H9N / 3 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
efsa openfoodtox 3 0 export repository
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| margin of safety | 1,500,000 other: | consumers | 0f06c0d1-439b-459e-8444-1f54884eaab3 | - |
| margin of safety | 1,500,000 other: | consumers | ad8a47a5-fd0a-4879-9cac-f0ed50e17992 | - |
| margin of safety | 1,500,000 other: | consumers | 6ba54ed5-b7fb-468d-bec8-7d00b07045ff | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
efsa openfoodtox 3 0 export repository
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| sub-chronic toxicity: oral | rat | oral: gavage | 37 other: | - |
| sub-chronic toxicity: oral | rat | oral: gavage | 37 other: | - |
| sub-chronic toxicity: oral | rat | oral: gavage | 37 other: | - |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to deliver a scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 24 flavouring substances in the Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 24 derivatives of pyridine, pyrrole, indole and quinoline belong to chemical group 28, Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.24, FGE.24Rev2, includes the assessment of new toxicity data on one supporting substance, 2-acetylpyrrole [FL-no: 14.047], to cover the re-evaluation of one candidate substance, 2-acetyl-5-methylpyrrole [FL-no: 14.085], for which additional data were required. Since the publication of the previous version of FGE.24, FGE.24Rev1, nine of the original 33 candidate substances [FL-no: 13.100, 14.002, 14.023, 14.094, 14.107, 14.138, 14.145, 14.163 and 14.169], for which additional data were required, are no longer supported by Industry for use as flavouring substances in Europe and will therefore not be considered any further. This revision of FGE.24, FGE.24Rev2, therefore deals only with 24 candidate substances. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate 31 flavouring substances in the Flavouring Group Evaluation FGE.24, using the procedure as referred to in the Commission Regulation EC No 1565/2000. These 31 flavouring substances belong to chemical group 28, Annex I of the Commission Regulation EC No 1565/2000. The present Flavouring Group Evaluation deals with 31 pyridine, pyrrole, indole and quinoline derivatives. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate 33 flavouring substances in the Flavouring Group Evaluation 24, Revision 1 (FGE.24Rev1), using the procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 33 flavouring substances belong to chemical group 28 of Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation deals with 33 pyridine, pyrrole, indole and quinoline derivatives. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate 31 flavouring substances in the Flavouring Group Evaluation FGE.24, using the procedure as referred to in the Commission Regulation EC No 1565/2000. These 31 flavouring substances belong to chemical group 28, Annex I of the Commission Regulation EC No 1565/2000. The present Flavouring Group Evaluation deals with 31 pyridine, pyrrole, indole and quinoline derivatives. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Scientific Panel is asked to evaluate 33 flavouring substances in the Flavouring Group Evaluation 24, Revision 1 (FGE.24Rev1), using the procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 33 flavouring substances belong to chemical group 28 of Annex I of the Commission Regulation (EC) No 1565/2000. The present Flavouring Group Evaluation deals with 33 pyridine, pyrrole, indole and quinoline derivatives. |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to deliver a scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to evaluate 24 flavouring substances in the Flavouring Group Evaluation 24, Revision 2 (FGE.24Rev2), using the Procedure as referred to in the Commission Regulation (EC) No 1565/2000. These 24 derivatives of pyridine, pyrrole, indole and quinoline belong to chemical group 28, Annex I of the Commission Regulation (EC) No 1565/2000. The present revision of FGE.24, FGE.24Rev2, includes the assessment of new toxicity data on one supporting substance, 2-acetylpyrrole [FL-no: 14.047], to cover the re-evaluation of one candidate substance, 2-acetyl-5-methylpyrrole [FL-no: 14.085], for which additional data were required. Since the publication of the previous version of FGE.24, FGE.24Rev1, nine of the original 33 candidate substances [FL-no: 13.100, 14.002, 14.023, 14.094, 14.107, 14.138, 14.145, 14.163 and 14.169], for which additional data were required, are no longer supported by Industry for use as flavouring substances in Europe and will therefore not be considered any further. This revision of FGE.24, FGE.24Rev2, therefore deals only with 24 candidate substances. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
page FAQ dataset
What is the regulatory limit for 2,4-Dimethylpyridine in cannabis?
2,4-Dimethylpyridine does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 2,4-Dimethylpyridine?
2,4-Dimethylpyridine does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 2,4-Dimethylpyridine?
2,4-Dimethylpyridine has 6 EFSA OpenFoodTox reference value rows in the cannabis database, including TTC Cramer Class II, margin of safety.
Is 2,4-Dimethylpyridine also regulated in cosmetics or food?
2,4-Dimethylpyridine has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.