OralParenteralTopicalDosed ingredient Cosmetic cross-reference

Sodium Chloride

CAS 7647-14-5

Sodium Chloride (CAS 7647-14-5) is a Phase 4 pharmaceutical compound with 1 bioactivity target and 8,600 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
1
SOURCE DrugCentral
Adverse signals
8,600
SOURCE IUPHAR/BPS
PubMed IDs
0
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Sodium Chloride
CAS Number
7647-14-5
UNII
451W47IQ8X
InChIKey
FAPWRFPIFSIZLT-UHFFFAOYSA-M
ChEMBL ID
CHEMBL1200574
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
dosed ingredientoralparenteraltopical
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 4 (Approved)
Approved or marketed human pharmaceutical use is represented in the source phase field.
ChEMBL CHEMBL1200574 | Small molecule
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →
SOURCE EMBL-EBI ChEMBL 1 bioactivity row

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- Ki 52000 nM 1 -
SOURCE DrugCentral 80 associations

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PTDrug AE LLRMedDRA
Myelosuppression 1645 3239.987 10028584
Infective pulmonary exacerbation of cystic fibrosis 717 1591.559 10070608
Hyperchloraemia 212 706.277 10020597
White blood cell count decreased 1462 703.827 10047942
Agranulocytosis 615 623.803 10001507
Peritonitis bacterial 338 611.478 10062070
Hereditary angioedema 308 578.827 10019860
Bone marrow failure 652 563.609 10065553
Drug ineffective 1537 493.732 10013709
Drug intolerance 111 457.114 10061822
Contraindicated product administered 27 427.236 10078504
Toxic anterior segment syndrome 182 427.234 10066366
Peritoneal dialysis complication 172 422.844 10067594
Rheumatoid arthritis 63 413.947 10039073
Joint swelling 147 412.875 10023232
Cystic fibrosis 199 412.355 10011762
Chills 1071 400.632 10008531
Synovitis 6 400.295 10042868
Neutrophil count decreased 722 373.716 10029366
Completed suicide 30 366.946 10010144
Pyrexia 2787 354.774 10037660
Arthropathy 67 351.826 10003285
Hand deformity 3 343.371 10061194
Therapeutic product effect decreased 44 335.368 10082201
Systemic lupus erythematosus 42 325.626 10042945
Alopecia 183 322.911 10001760
Treatment failure 74 316.903 10066901
Chest discomfort 878 316.364 10008469
Fungal peritonitis 112 306.33 10061138
Arthralgia 698 288.382 10003239
Peritonitis 342 286.946 10034674
Glossodynia 34 285.476 10018388
Macular degeneration 291 237.972 10025409
Hepatic function abnormal 511 237.352 10019670
Infusion site extravasation 210 217.35 10064774
Cytokine release syndrome 318 216.677 10052015
Incorrect drug administration rate 140 212.842 10064306
Toxicity to various agents 379 209.381 10070863
Device interaction 75 205.891 10012586
Hypernatraemia 206 205.657 10020679
Musculoskeletal stiffness 120 194.331 10052904
Hyperpyrexia 134 191.809 10020741
Drug interaction 397 191.616 10013710
Pericarditis 42 186.495 10034484
Sepsis 1209 182.911 10040047
Duodenal ulcer perforation 3 181.83 10013849
Pneumonia 2458 181.662 10035664
Psoriatic arthropathy 13 180.612 10037162
Temperature intolerance 169 176.849 10057040
Drug abuse 60 172.274 10013654

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE NLM RxNorm 5 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

NameRxCUI TypeSource
Sodium Chloride 9863 SU MTHSPL
sodium chloride 9863 SU MTHSPL
SODIUM CHLORIDE 9863 SU MTHSPL
Sodium chloride 9863 SU MTHSPL
sodium chloride 9863 IN RXNORM
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Sodium Chloride used for in pharmaceutical contexts?

Sodium Chloride (CAS 7647-14-5) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Sodium Chloride?

Sodium Chloride has 8,600 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Myelosuppression, Infective pulmonary exacerbation of cystic fibrosis, Hyperchloraemia, White blood cell count decreased, Agranulocytosis. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Sodium Chloride also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Sodium Chloride with EU status "permitted".

What clinical phase is Sodium Chloride in?

Sodium Chloride is rendered with ChEMBL max phase 4 (approved).