Is ZINC FORMALDEHYDE SULFOXYLATE safe in cosmetics?
ZINC FORMALDEHYDE SULFOXYLATE has a safety rating of "MODERATE" in our database. EU status: restricted. 2 toxicological study endpoint(s) are available in our database.
ZINC FORMALDEHYDE SULFOXYLATE
Also known as: Zinc, bis[1-(hydroxy-κO)methanesulfinato-κO]-, (T-4)-, Zinc formaldehydesulfoxylate, Zinc, bis(hydroxymethanesulfinato-OS,O1)-, (T-4)-, Zinc, bis[(hydroxy-κO)methanesulfinato-κO]-, (T-4)-, Methanesulfinic acid, hydroxy-, zinc complex (+12 more)
ZINC FORMALDEHYDE SULFOXYLATE (CAS 24887-06-7) is a cosmetic cosmetic ingredient functioning as Reducing. NOAEL 31.52 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max III/24. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 24887-06-7 →
Auto-generated CPSR Part A draft with source citations
Function
Reducing
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
zinc hydroxymethanesulfinate
InChIKey
CAAIULQYGCAMCD-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
III/24
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for ZINC FORMALDEHYDE SULFOXYLATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =300 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for ZINC FORMALDEHYDE SULFOXYLATE across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Reducing agent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for ZINC FORMALDEHYDE SULFOXYLATE.
Regulatory Flags
cosing-sourced
eu-restricted
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to ZINC FORMALDEHYDE SULFOXYLATE by CAS number or substance name.
Studies
2
Lowest NOAEL
300 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Zinc, bis[1-(hydroxy-κO)methanesulfinato-κO]-, (T-4)-
Zinc formaldehydesulfoxylate
Zinc, bis(hydroxymethanesulfinato-OS,O1)-, (T-4)-
Zinc, bis[(hydroxy-κO)methanesulfinato-κO]-, (T-4)-
Methanesulfinic acid, hydroxy-, zinc complex
Blankit D
C.I. Reducing Agent 6
Decroline
Decroline Soluble Conc.
Decroline soluble
Methanesulfinic acid, hydroxy-, zinc salt (2:1)
Parolite
Protolin SX
Redol ZB
Redusol Z
Safolin
EINECS No.: 246-515-6
Chemical Function
Reducing agent
Regulatory Lists
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is ZINC FORMALDEHYDE SULFOXYLATE allowed in the EU?
ZINC FORMALDEHYDE SULFOXYLATE EU regulatory status: restricted. Maximum allowed concentration: III/24. This is based on EU Regulation 1223/2009 and its amendments.
What does ZINC FORMALDEHYDE SULFOXYLATE do in cosmetics?
ZINC FORMALDEHYDE SULFOXYLATE functions as: Reducing. It is classified as a cosmetic ingredient in our database. CAS number: 24887-06-7.
What is the NOAEL for ZINC FORMALDEHYDE SULFOXYLATE?
The NOAEL (No Observed Adverse Effect Level) for ZINC FORMALDEHYDE SULFOXYLATE is =300 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Compliance Tools
Check ZINC FORMALDEHYDE SULFOXYLATE compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
DITHIOTHREITOL
Good
Same category
Hair Waving Or Straightening, Reducing
NINHYDRIN
Good
Same category
Reducing
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
ZINC
Good
Browse nearby
Antioxidant
ZINC ACETATE
Moderate
Browse nearby
Antimicrobial
ZINC ACETYLMETHIONATE
Good
Browse nearby
Skin Conditioning
ZINC ADENOSINE TRIPHOSPHATE
Moderate
Browse nearby
Antioxidant, Skin Conditioning
1,4-Butanediol
Poor
Same EU status
Solvent, humectant, viscosity control...
1-Acetoxy-2-Methylnaphthalene
Good
Same EU status
Hair dyeing; colours the hair
1-Hexyl 4,5-Diamino Pyrazole Sulfate
Good
Same EU status
Hair dyeing — oxidative hair colourin...
Is ZINC FORMALDEHYDE SULFOXYLATE in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for ZINC FORMALDEHYDE SULFOXYLATE in your formulation.