Is Xylene Diisocyanate safe in cosmetics?
Xylene Diisocyanate has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Xylene Diisocyanate
INCI: XYLENE DIISOCYANATE
Xylene Diisocyanate (CAS 3634-83-1 (m-XDI); 25854-16-4 (mixture)) is a cosmetic cosmetic ingredient functioning as Crosslinking agent / polymer precursor (not a direct cosmetic functional. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 3634-83-1 (m-XDI); 25854-16-4 (mixture) →
Auto-generated CPSR Part A draft with source citations
Function
Crosslinking agent / polymer precursor (not a direct cosmetic functional ingredient)
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not permitted in cosmetic formulations; classified as hazardous industrial chemical
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Xylene Diisocyanate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Xylene Diisocyanate.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Xylene Diisocyanate allowed in the EU?
Xylene Diisocyanate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Xylene Diisocyanate do in cosmetics?
Xylene Diisocyanate functions as: Crosslinking agent / polymer precursor (not a direct cosmetic functional ingredient). It is classified as a cosmetic ingredient in our database. CAS number: 3634-83-1 (m-XDI); 25854-16-4 (mixture).
Compliance Tools
Check Xylene Diisocyanate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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