NOAEL Studies
Cosmetic Ingredient
Undecane NOAEL Studies
INCI: UNDECANE
CAS: 1120-21-4
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip 6 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | >=1000 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=dcb28cae-8211-4ba9-a639-7be385adde5d.i6z; document=dd21f4e8-3a4d-483e-a5c3-a5e45e7db797_dcb28cae-8211-4ba9-a639-7be385adde5d.i6d; document_key=dd21f4e8-3a4d-483e-a5c3-a5e45e7db797/dcb28cae-8211-4ba9-a639-7be385adde5d; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1996; basis=other:; key_result=false; entry_uuid=6865a59d-4655-4798-b2a9-320b537ae240 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | >=5000 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=dcb28cae-8211-4ba9-a639-7be385adde5d.i6z; document=7cd1b73b-9c08-4b57-b4e1-c138dcf81b3f_dcb28cae-8211-4ba9-a639-7be385adde5d.i6d; document_key=7cd1b73b-9c08-4b57-b4e1-c138dcf81b3f/dcb28cae-8211-4ba9-a639-7be385adde5d; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1991-10-24; basis=other:; key_result=false; entry_uuid=cfc78609-4e3f-4591-b87f-edc023502198 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | >=1000 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=dcb28cae-8211-4ba9-a639-7be385adde5d.i6z; document=dd21f4e8-3a4d-483e-a5c3-a5e45e7db797_dcb28cae-8211-4ba9-a639-7be385adde5d.i6d; document_key=dd21f4e8-3a4d-483e-a5c3-a5e45e7db797/dcb28cae-8211-4ba9-a639-7be385adde5d; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1996; basis=other:; key_result=false; entry_uuid=6865a59d-4655-4798-b2a9-320b537ae240 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | >=5000 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=dcb28cae-8211-4ba9-a639-7be385adde5d.i6z; document=7cd1b73b-9c08-4b57-b4e1-c138dcf81b3f_dcb28cae-8211-4ba9-a639-7be385adde5d.i6d; document_key=7cd1b73b-9c08-4b57-b4e1-c138dcf81b3f/dcb28cae-8211-4ba9-a639-7be385adde5d; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1991-10-24; basis=other:; key_result=false; entry_uuid=cfc78609-4e3f-4591-b87f-edc023502198 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | >=1000 | mg/kg bw/day | rat | oral: gavage | - | one-generation reproductive toxicity | dossier=dcb28cae-8211-4ba9-a639-7be385adde5d.i6z; document=dd21f4e8-3a4d-483e-a5c3-a5e45e7db797_dcb28cae-8211-4ba9-a639-7be385adde5d.i6d; document_key=dd21f4e8-3a4d-483e-a5c3-a5e45e7db797/dcb28cae-8211-4ba9-a639-7be385adde5d; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1996; basis=other:; key_result=false; entry_uuid=6865a59d-4655-4798-b2a9-320b537ae240 |
| ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip | NOAEL | >=5000 | mg/kg bw/day | rat | oral: gavage | - | sub-chronic toxicity: oral | dossier=dcb28cae-8211-4ba9-a639-7be385adde5d.i6z; document=7cd1b73b-9c08-4b57-b4e1-c138dcf81b3f_dcb28cae-8211-4ba9-a639-7be385adde5d.i6d; document_key=7cd1b73b-9c08-4b57-b4e1-c138dcf81b3f/dcb28cae-8211-4ba9-a639-7be385adde5d; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1991; ReportDate=1991-10-24; basis=other:; key_result=false; entry_uuid=cfc78609-4e3f-4591-b87f-edc023502198 |
NTP_ICE_acute_inhalation 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_inhalation | LC50 | >2.824 | mg/L | - | Inhalation | Duration=8 hr | In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity | sheet=Data; excel_row=5030; Record_ID=acute_inhalation_3150; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID9021689; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=2.824; Response_Unit=mg/L; Reference=ChemIDplus; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9021689 |
NTP_ICE_acute_oral 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_oral | LD50 | >15000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_1239; row=15422; data_type=In Vivo; mixture=Chemical; chemical_name=Undecane; preferred_name=Undecane; dtxsid=DTXSID9021689; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9021689; source_file=acute_oral.xlsx |
| NTP_ICE_acute_oral | LD50 | >5000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_1237; row=15423; data_type=In Vivo; mixture=Chemical; chemical_name=Undecane; preferred_name=Undecane; dtxsid=DTXSID9021689; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9021689; source_file=acute_oral.xlsx |
NTP_ICE_endocrine 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_endocrine | Model Score | 0 | unitless | - | - | - | ARPathway2016; AR Pathway Model, Antagonist | sheet=Integrated_approaches; excel_row=16254; RecordID=ARPathway2016_591; DatasetName=ARPathway2016; DTXSID=DTXSID9021689; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID9021689 |
ToxValDB_ECHA_IUCLID 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | =1000 | mg/kg bw/day | Rat | oral | - | short-term | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca25e4b0a7c65d2206ba; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/2075/7/6/2?documentUUID=dcb28cae-8211-4ba9-a639-7be385adde5d; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID:15845871:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ad5e47b7ba1220058f5d146b2b329625 |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | JV0QT00NUE | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C11H24","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"JV0QT00NUE"} |
| openFDA substances | FDA UNII substance identifier | JV0QT00NUE | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C11H24","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"JV0QT00NUE"} |
| openFDA substances | FDA UNII substance identifier | JV0QT00NUE | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C11H24","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"JV0QT00NUE"} |
| openFDA substances | FDA UNII substance identifier | JV0QT00NUE | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C11H24","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"JV0QT00NUE"} |