Is Undecane safe in cosmetics?
Undecane has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Undecane
Also known as: N 11, NSC 66159, 4-01-00-00487, BRN 1697099, EINECS 214-300-6 (+1 more)
INCI: UNDECANE
Undecane (CAS 1120-21-4) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Emollient, Volatile lightweight emollient. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 1120-21-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Undecane is classified GHS Danger (H304, H226, H335, H227) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin Conditioning, Emollient, Volatile lightweight emollient
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
undecane
InChIKey
RSJKGSCJYJTIGS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA prohibitions or restrictions. Listed in TSCA inventory.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Undecane.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Undecane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Undecane across SCCS product categories, with measured dermal absorption where available.
EPA ToxValDB — Toxicity Values
2 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg-day | Rat | oral | - | ECHA IUCLID |
| LC50 | >5651.59 mg/m3 | Rat | inhalation | - | ChemIDplus |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
Exposure to undecane during industrial use causes eye and skin irritation. It is irritating to mucous membranes and the upper respiratory tract.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Softener and conditioner
Solvent
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Undecane.
Regulatory Flags
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Undecane by CAS number or substance name.
Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
N 11
NSC 66159
4-01-00-00487
BRN 1697099
EINECS 214-300-6
UNII-JV0QT00NUE
Chemical Function
Softener and conditioner
Solvent
Fragrance
Regulatory Lists
detected; Other direct contact consumer goods; Other indirect contact consumer goods
fracking; water
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe
Cleaning products and household care - laundry and fabric treatment - laundry stain remover; detected; Europe
consumer_product; detected; Europe
air; Cleaning products and household care - laundry and fabric treatment; detected; emissions
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe
air; detected; emissions; Europe; Other direct contact consumer goods
detected; Europe; Other direct contact consumer goods
detected; Europe; Other direct contact consumer goods
air; detected; emissions; Europe; Toys and children's products
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
UNDECANE
ChEMBL ID
CHEMBL132474
Frequently Asked Questions
Is Undecane allowed in the EU?
Undecane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Undecane do in cosmetics?
Undecane functions as: Skin Conditioning, Emollient, Volatile lightweight emollient. It is classified as a cosmetic ingredient in our database. CAS number: 1120-21-4.
What is the NOAEL for Undecane?
The NOAEL (No Observed Adverse Effect Level) for Undecane is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Undecane used outside cosmetics?
Undecane also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Undecane have different safety status in cosmetics vs industrial chemicals?
Undecane is classified GHS Danger (H304, H226, H335, H227) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Undecane compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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