Is Tyrosine safe in cosmetics?
Tyrosine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Tyrosine
INCI: TYROSINE
Tyrosine (CAS 60-18-4 (L-Tyrosine); 556-03-6 (DL-Tyrosine)) is a cosmetic cosmetic ingredient functioning as Antistatic, fragrance ; also used for skin conditioning and tanning enhancement. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 60-18-4 (L-Tyrosine); 556-03-6 (DL-Tyrosine) →
Auto-generated CPSR Part A draft with source citations
Function
Antistatic, fragrance ; also used for skin conditioning and tanning enhancement (melanin precursor)
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Generally Recognized as Safe (GRAS) as an amino acid; permissible in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tyrosine.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
4 property records from structured ingredient metadata.
acne
{"cas_number": "60-18-4", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_ac…
anti_aging
{"anti_aging_claim": "brightening precursor", "mechanism_of_action": "Building block for proteins, NMF component", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "4-8", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Int J Cosmet Sci", "impro…
self_tanning
{"cas_number": "60-18-4", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "48.0", "full_color_development_hours": "168", "color_duration_days": "14", "color_depth": "adjustable", "undertone": "natural", "color_uniformity": "excellent", "fade_pattern": "even", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_p…
sensory
{"silky": "powdery", "smooth, glides easily": "smooth, melanin precursor", "dry-touch, non-greasy": "protected, even", "instant": "moderate", "low": "low", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.46", "transparent": "opaque", "colorless": "white", "excellent": "fair", "light": "light", "synthetic": "biotechnology"}
Expert Verdict
Expert safety assessment and concern-level summary for Tyrosine.
Regulatory Flags
fragrance-component
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Tyrosine by CAS number or substance name.
Studies
6
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
600 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Frequently Asked Questions
Is Tyrosine allowed in the EU?
Tyrosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tyrosine do in cosmetics?
Tyrosine functions as: Antistatic, fragrance ; also used for skin conditioning and tanning enhancement (melanin precursor). It is classified as a cosmetic ingredient in our database. CAS number: 60-18-4 (L-Tyrosine); 556-03-6 (DL-Tyrosine).
Compliance Tools
Check Tyrosine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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