Is Trihydroxystearin safe in cosmetics?
Trihydroxystearin has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Trihydroxystearin
Also known as: EINECS 205-364-6, Glycerol tris(12-hydroxystearate), Glyceryl tris(12-hydroxystearate), 12-Hydroxyoctadecanoic acid, glyceryl ester, 12-Hydroxyoctadecanoic acid, triester with glycerol (+5 more)
INCI: TRIHYDROXYSTEARIN
Trihydroxystearin (CAS 139-44-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning, viscosity controlling, thixotropic thickener. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 139-44-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, viscosity controlling, thixotropic thickener
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,3-bis(12-hydroxyoctadecanoyloxy)propyl 12-hydroxyoctadecanoate
InChIKey
WCOXQTXVACYMLM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics; no restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trihydroxystearin.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-adhesive/cohesive
Humectant
Lubricating agent
Processing aids not otherwise specified
Softener and conditioner
Solvent
Thickening agent
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for Trihydroxystearin.
Known Synonyms
EINECS 205-364-6
Glycerol tris(12-hydroxystearate)
Glyceryl tris(12-hydroxystearate)
12-Hydroxyoctadecanoic acid, glyceryl ester
12-Hydroxyoctadecanoic acid, triester with glycerol
12-Hydroxystearic acid triglyceride
NSC 2389
Octadecanoic acid, 12-hydroxy-, triester with glycerol
Thixin R
UNII-06YD7896S3
Chemical Function
Softener and conditioner
Viscosity modifier
Solvent
Humectant
Thickening agent
Processing aids not otherwise specified
Anti-adhesive/cohesive
Lubricating agent
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Trihydroxystearin allowed in the EU?
Trihydroxystearin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trihydroxystearin do in cosmetics?
Trihydroxystearin functions as: Skin conditioning, viscosity controlling, thixotropic thickener. It is classified as a cosmetic ingredient in our database. CAS number: 139-44-6.
Is Trihydroxystearin used outside cosmetics?
Trihydroxystearin also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Trihydroxystearin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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