Is Tetrapeptide-7 safe in cosmetics?
Tetrapeptide-7 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Tetrapeptide-7
INCI: TETRAPEPTIDE-7 (COMMONLY USED AS PALMITOYL TETRAPEPTIDE-7)
Tetrapeptide-7 (CAS 221227-05-0 (as Palmitoyl Tetrapeptide-7, the commercially used form)) is a cosmetic cosmetic ingredient functioning as Anti-inflammatory (decreases IL-6 secretion); skin conditioning; humectant;. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
221227-05-0 (as Palmitoyl Tetrapeptide-7, the commercially used form)
View industrial chemical safety profile →
Function
Anti-inflammatory (decreases IL-6 secretion); skin conditioning; humectant; reduces inflammation after UVB exposure; stimulates collagen VII, laminin IV and V production
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA monograph; CIR (Cosmetic Ingredient Review) concluded safe as used in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrapeptide-7.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Tetrapeptide-7.
Frequently Asked Questions
Is Tetrapeptide-7 allowed in the EU?
Tetrapeptide-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrapeptide-7 do in cosmetics?
Tetrapeptide-7 functions as: Anti-inflammatory (decreases IL-6 secretion); skin conditioning; humectant; reduces inflammation after UVB exposure; stimulates collagen VII, laminin IV and V production. It is classified as a cosmetic ingredient in our database. CAS number: 221227-05-0 (as Palmitoyl Tetrapeptide-7, the commercially used form).
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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