Is Tetramethylhexanal safe in cosmetics?
Tetramethylhexanal has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Tetramethylhexanal
INCI: TETRAMETHYLHEXANAL
Tetramethylhexanal (CAS Likely 5765-44-6 (2,2,4,4-tetramethylhexanal) or positional isomer — verify exact substitution pattern) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient — aldehyde with fresh/green character. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Likely 5765-44-6 (2,2,4,4-tetramethylhexanal) or positional isomer — verify exact substitution pattern
View industrial chemical safety profile →
Function
Fragrance ingredient — aldehyde with fresh/green character
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted under general fragrance provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetramethylhexanal.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Tetramethylhexanal.
Regulatory Flags
potential-allergen
fragrance-component
Frequently Asked Questions
Is Tetramethylhexanal allowed in the EU?
Tetramethylhexanal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetramethylhexanal do in cosmetics?
Tetramethylhexanal functions as: Fragrance ingredient — aldehyde with fresh/green character. It is classified as a cosmetic ingredient in our database. CAS number: Likely 5765-44-6 (2,2,4,4-tetramethylhexanal) or positional isomer — verify exact substitution pattern.
Compliance Tools
Check Tetramethylhexanal compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent
Same category
Fragrance
Acetoin
Excellent
Same category
Skin conditioning, fragrance
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
TETRACARBOXYMETHYL NARINGENINCHALCONE
Good
Browse nearby
Skin Conditioning
TETRADECYLPROPIONATES
Good
Browse nearby
Skin Conditioning, Skin Conditioning ...
TETRAHYDRO-6-PENT-2-ENYL-PYRAN-2-ONE
Good
Browse nearby
Perfuming
Is Tetramethylhexanal in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Tetramethylhexanal in your formulation.