Is Tetrahydrogeranial safe in cosmetics?
Tetrahydrogeranial has a safety rating of "GOOD" in our database. EU status: restricted. US status: restricted.
Good
Cosmetic Ingredient
Tetrahydrogeranial
Also known as: Octanal, 3,7-dimethyl-, 4-01-00-03371, BRN 1721497, Dihydrocitronellal, 6,7-Dihydrocitronellal (+2 more)
INCI: TETRAHYDROGERANIAL (SYNONYM: DIHYDROCITRONELLAL; 3,7-DIMETHYLOCTANAL)
Tetrahydrogeranial (CAS 5988-91-0) is a cosmetic cosmetic ingredient functioning as Fragrance Ingredient. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 5988-91-0 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance Ingredient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3,7-dimethyloctanal
InChIKey
UCSIFMPORANABL-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not specifically restricted; permitted as fragrance ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrahydrogeranial.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
2176
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
3,7-DIMETHYLOCTANAL | 2012 | No safety concern at current levels of intake when used as a flavouring agent | TRS 974-JECFA 76
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Tetrahydrogeranial.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
Octanal, 3,7-dimethyl-
4-01-00-03371
BRN 1721497
Dihydrocitronellal
6,7-Dihydrocitronellal
EINECS 227-810-9
UNII-F32WFZ5HGW
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3188979
Frequently Asked Questions
Is Tetrahydrogeranial allowed in the EU?
Tetrahydrogeranial EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrahydrogeranial do in cosmetics?
Tetrahydrogeranial functions as: Fragrance Ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 5988-91-0.
Is Tetrahydrogeranial used outside cosmetics?
Tetrahydrogeranial also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Tetrahydrogeranial compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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