Is Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) safe in cosmetics?
Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®)
INCI: TETRAHYDRO-METHYL-PROPYL-PYRAN-4-OLACETATE
Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) (CAS 131766-73-9) is a cosmetic cosmetic ingredient functioning as Fragrance – fruity, floral, herbal, clary sage-like. NOAEL 600 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 131766-73-9 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance – fruity, floral, herbal, clary sage-like
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(4-methyl-2-propyloxan-4-yl) acetate
InChIKey
GURYYNWDVKXZAT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; TSCA listed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®).
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) across SCCS product categories, with measured dermal absorption where available.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Warning
Pictograms
Harmful / Irritant
Hazard Class and Category
Skin Sens. 1
Hazard Statements
- H317 May cause an allergic skin reaction
Inserted via ATP: CLP00
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
Ceased manufacture
Substance Type
SUBSTANCE
SVHC Candidate
No
Hazard classification: Restricted (Annex XVII)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®).
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed_with_terms
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.
Frequently Asked Questions
Is Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) allowed in the EU?
Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) do in cosmetics?
Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) functions as: Fragrance – fruity, floral, herbal, clary sage-like. It is classified as a cosmetic ingredient in our database. CAS number: 131766-73-9.
Is Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) used outside cosmetics?
Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Tetrahydro-methyl-propyl-pyran-4-olacetate (Clarycet®) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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TETRAHYDRO-METHYL-PROPYL-PYRAN-4-OLACETATE
Good
Chemical family
Perfuming
TETRACARBOXYMETHYL NARINGENINCHALCONE
Good
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Skin Conditioning
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