NOAEL Studies
Cosmetic Ingredient
Styralyl Alcohol NOAEL Studies
INCI: STYRALYL ALCOHOL (Α-METHYLBENZYL ALCOHOL; 1-PHENYLETHANOL)
CAS: 98-85-1
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
COSMOS_DB 5 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| COSMOS_DB | NOAEL | 93 | mg/kg bw/day | rat | oral | 89 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 375 | mg/kg bw/day | mouse | oral | 89 day | Subchronic | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 750 | mg/kg bw/day | mouse | oral | 721 day | Carcinogenicity | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 1000 | mg/kg bw/day | mouse | oral | 16 day | Short Term Toxicity | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
| COSMOS_DB | NOAEL | 2000 | mg/kg bw/day | rat | oral | 16 day | Short Term Toxicity | US FDA CFSAN PAFA; US FDA CFSAN PAFA Study |
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx | LOAEL | =93 | mg/kg bw/day | Rat | oral: gavage | 91 days | subchronic | EFSA FEEDAP - 2016 - OutputID 2863 - Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species - doi:10.2903/j.efsa.2016.4557 |
| EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx | LOAEL | =93 | mg/kg bw/day | Rat | oral: gavage | 91 days | subchronic | EFSA FEEDAP - 2016 - OutputID 2863 - Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species - doi:10.2903/j.efsa.2016.4557 |
| EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx | NOAEL | =50 | mg/kg bw/day | Rat | oral: feed | 91 days | subchronic | EFSA FEEDAP - 2016 - OutputID 2863 - haematology - hemopoietic - Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species - doi:10.2903/j.efsa.2016.4557 |
| EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx | NOAEL | =50 | mg/kg bw/day | Rat | oral: feed | 91 days | subchronic | EFSA FEEDAP - 2016 - OutputID 2863 - haematology - hemopoietic - Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species - doi:10.2903/j.efsa.2016.4557 |
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx | ADI | =0.1 | mg/kg bw/day | Consumers | - | - | ADI | EFSA FEEDAP - 2016 - OutputID 2863 - Consumers - Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species - doi:10.2903/j.efsa.2016.4557 |
| EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx | ADI | =0.1 | mg/kg bw/day | Consumers | - | - | ADI | EFSA FEEDAP - 2016 - OutputID 2863 - Consumers - Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species - doi:10.2903/j.efsa.2016.4557 |
NTP_ICE_acute_oral 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_oral | LD50 | =400 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | NLM ChemIDplus TEST (undated); record_id=acute_oral_11917; row=2091; data_type=In Vivo; mixture=Chemical; chemical_name=alpha-Methylbenzyl alcohol; preferred_name=alpha-Methylbenzyl alcohol; dtxsid=DTXSID1020859; url=https://chem.nlm.nih.gov/chemidplus/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020859; url_cebs=https://doi.org/10.22427/NTP-DATA-DTXSID1020859; source_file=acute_oral.xlsx |
NTP_ICE_cancer 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_cancer | Top dose | 750 | mg/kg bw/day | Mouse | Gavage | - | In Vivo; NTP Carcinogenicity | sheet=Data; excel_row=1413; Record_ID=cancer_5376; Data_Type=In Vivo; Formulation_Name=Alpha-Methylbenzyl Alcohol; Mixture=Chemical; DTXSID=DTXSID1020859; Assay=NTP Carcinogenicity; Endpoint=Top dose; Response=750; Response_Unit=mg/kg/day; Species=Mouse; Strain=B6C3F1; Sex=Female; Route=Gavage; Reference=TR-369; URL=https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr369/index.html; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020859; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1020859 |
NTP_ICE_skin_sensitization 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_skin_sensitization | Incidence of positive responses | 0 | % | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=11522; Record_ID=skin_sensitization_invivo_2503; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1020859; Assay=Human Maximization Test; Endpoint=Incidence of positive responses; Response=0; Response_Unit=%; Species=Human; Route=Dermal; Reference=Kligman 1973: report to RlFM|Opdyke 1974; Not available; 10.1016/0015-6264(74)90221-1; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020859; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1020859 |
| NTP_ICE_skin_sensitization | Induction dose per skin area | 5184 | ug/cm2 | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=11520; Record_ID=skin_sensitization_invivo_2503; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1020859; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=5184; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Kligman 1973: report to RlFM|Opdyke 1974; Not available; 10.1016/0015-6264(74)90221-1; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020859; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1020859 |
| NTP_ICE_skin_sensitization | Relative reliability score | 3 | unitless | Human | Dermal | - | In Vivo; HPPT2020WIP; Human Maximization Test | sheet=Data_invivo; excel_row=11526; Record_ID=skin_sensitization_invivo_2503; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=8.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID1020859; Assay=Human Maximization Test; Endpoint=Relative reliability score; Response=3; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Kligman 1973: report to RlFM|Opdyke 1974; Not available; 10.1016/0015-6264(74)90221-1; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID1020859; URL_CEBS=https://doi.org/10.22427/NTP-DATA-DTXSID1020859 |
ToxValDB_ECHA_IUCLID 13 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | LOAEL | =46.9 | mg/kg bw/day | Mouse | oral | subchronic; 13 weeks | subchronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf90e4b0a7c65d1ce858; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15850069:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_4eed4865929af16c387acbb91865b8f7 |
| ToxValDB_ECHA_IUCLID | LOAEL | =187.5 | mg/kg bw/day | Mouse | oral | subchronic; 13 weeks | subchronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf90e4b0a7c65d1ce858; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15850070:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_0d98038f764bc7382c0f925b3f2a6e95 |
| ToxValDB_ECHA_IUCLID | LOAEL | =375 | mg/kg bw/day | Rat | oral | chronic; 2 years | chronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf8fe4b0a7c65d1ce851; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15850067:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_18c06571fccd0a982afb00ed7ff74673 |
| ToxValDB_ECHA_IUCLID | LOAEL | =508 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c977e4b0a7c65d21d091; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/9/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; TOXICOLOGICAL_EFFECT=P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=reproduction; STUDY_GROUP=ECHA IUCLID:15857666:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_bea6d5668546e1f2b631dc0bea602e0e |
| ToxValDB_ECHA_IUCLID | LOAEL | =750 | mg/kg bw/day | Rat | oral | chronic; 2 years | chronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf8fe4b0a7c65d1ce851; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15834735_15850068:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_efa6ede0db370ba0bd94908558b98933 |
| ToxValDB_ECHA_IUCLID | LOAEL | =1400 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c977e4b0a7c65d21d076; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/9/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856300_15857471_15857580_15857728:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_715cfbb7d2b4cc77a8aa682693dbd6e5 |
| ToxValDB_ECHA_IUCLID | NOAEL | =43 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c977e4b0a7c65d21d09c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/9/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; TOXICOLOGICAL_EFFECT=P0: clinical signs|P0: mortality|P0: body weight and weight gain|P0: organ weights and organ / body weight ratios|P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|mortality/survival|organ weight|reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856300_15857471_15857580_15857728:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_06a31bd8e0d9a4f3ba7c58b29ef6dda5 |
| ToxValDB_ECHA_IUCLID | NOAEL | =70 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c977e4b0a7c65d21d063; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/9/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; TOXICOLOGICAL_EFFECT=P0: clinical signs|P0: mortality|P0: dermal irritation|P0: body weight and weight gain|P0: food consumption and compound intake|P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|food and/or water consumption|mortality/survival|reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856300_15857471_15857580_15857728:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9eb74c3596bc88bb09ab7a26fd1a0b36 |
| ToxValDB_ECHA_IUCLID | NOAEL | =93 | mg/kg bw/day | Rat | oral | subchronic; 13 weeks | subchronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf90e4b0a7c65d1ce85c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15836139_15850071:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_aee162c207c6065a93bbe52daab1cd73 |
| ToxValDB_ECHA_IUCLID | NOAEL | =140 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c977e4b0a7c65d21d076; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/9/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15855486:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ba69824828c53a47638617e88b03b5f2 |
| ToxValDB_ECHA_IUCLID | NOAEL | =430 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c977e4b0a7c65d21d088; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/9/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; TOXICOLOGICAL_EFFECT=P0: clinical signs|P0: mortality|P0: body weight and weight gain|P0: food consumption and compound intake|P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|food and/or water consumption|mortality/survival|reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15856300_15857471_15857580_15857728:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_751015c349af67ccc4f05f90e2122ddb |
| ToxValDB_ECHA_IUCLID | NOAEL | =500 | mg/kg bw/day | Mouse | oral | short-term; 16 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cc35e4b0a7c65d2297a5; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15850072:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_fede263bc6893aca246d839f2a716c08 |
| ToxValDB_ECHA_IUCLID | NOAEL | =1000 | mg/kg bw/day | Rat | oral | short-term; 16 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cc35e4b0a7c65d2297ac; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/31233/7/6/2?documentUUID=2d0c8ff2-90f1-4764-b56f-dd13dfe3ec42; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15850073:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_919b65135278fb86bb03fb9b22c43823 |
ToxValDB_EFSA 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_EFSA | NOAEL | =50 | mg/kg bw/day | Rat | oral | subchronic; 13 weeks | subchronic | LONG_REF=EFSA FEEDAP (2016). Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species. doi:10.2903/j.efsa.2016.4557.; TITLE=Safety and efficacy of aromatic ketones, secondary alcohols and related esters belonging to chemical group 21 when used as flavourings for all animal species; AUTHOR=EFSA FEEDAP; DOI=doi:10.2903/j.efsa.2016.4557; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2016; ORIGINAL_YEAR=2016; TOXICOLOGICAL_EFFECT=hematological; TOXICOLOGICAL_EFFECT_CATEGORY=hematology; STUDY_GROUP=EFSA:15621557:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b4c8aa1429cdf4e356cda33d6624bf7f |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =4.66 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634103:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d6139afa5d9568a8fa0d3bbffd32b242 |
ToxValDB_WHO_JECFA_ADI 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_WHO_JECFA_ADI | ADI | <=0.1 | mg/kg | Human | oral | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/650af0bfe4b0d99f5a86e1b9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://apps.who.int/food-additives-contaminants-jecfa-database/; SUBSOURCE_URL=https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/4134; YEAR=2001; ORIGINAL_YEAR=2001; STUDY_GROUP=WHO JECFA ADI:15715241:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e17396ae83b38aca41d7c51591f19c52 |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | E6O895DQ52 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C8H10O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E6O895DQ52"} |
| openFDA substances | FDA UNII substance identifier | E6O895DQ52 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C8H10O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E6O895DQ52"} |
| openFDA substances | FDA UNII substance identifier | E6O895DQ52 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C8H10O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E6O895DQ52"} |
| openFDA substances | FDA UNII substance identifier | E6O895DQ52 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C8H10O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E6O895DQ52"} |