Is Stevioside safe in cosmetics?
Stevioside has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Stevioside
Also known as: Stevian 50, 4-17-00-03618, BRN 0077427, EINECS 260-975-5, UNII-0YON5MXJ9P (+3 more)
INCI: STEVIOSIDE
Stevioside (CAS 57817-89-7) is a cosmetic cosmetic ingredient functioning as Fragrance, Oral care. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 57817-89-7 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance, Oral care
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
InChIKey
UEDUENGHJMELGK-HYDKPPNVSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS as high-purity steviol glycoside for food use; cosmetic use permitted under general provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Stevioside.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
STEVIOSIDE | 2023 | 0–4 mg/kg bw | Considered for specification only. | TRS 1050-JECFA 96/37 | FAS 73 JECFA 82/181
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Expert Verdict
Expert safety assessment and concern-level summary for Stevioside.
Regulatory Flags
fragrance-component
Known Synonyms
Stevian 50
4-17-00-03618
BRN 0077427
EINECS 260-975-5
UNII-0YON5MXJ9P
1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv.
1,2-Stevioside
E 960
Chemical Function
Deodorizer
Flavouring and nutrient
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
STEVIOSIDE
ChEMBL ID
CHEMBL444122
Max Phase
1
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Steviol glycosides (from fermentation)
E Number
E960b
ADI
4 mg/kg bw
Food Category
sweetener
Frequently Asked Questions
Is Stevioside allowed in the EU?
Stevioside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Stevioside do in cosmetics?
Stevioside functions as: Fragrance, Oral care. It is classified as a cosmetic ingredient in our database. CAS number: 57817-89-7.
Is Stevioside used outside cosmetics?
Stevioside also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Stevioside compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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