Is Sodium Glycinate safe in cosmetics?
Sodium Glycinate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Sodium Glycinate
INCI: SODIUM GLYCINATE
Sodium Glycinate (CAS 6000-44-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning. NOAEL 2000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 6000-44-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
sodium 2-aminoacetate
InChIKey
WUWHFEHKUQVYLF-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; CIR reviewed and found safe in current use concentrations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Glycinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Sodium Glycinate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Glycinate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Sodium Glycinate by CAS number or substance name.
Studies
12
Lowest NOAEL
560 mg/kg bw/day
Highest NOAEL
2000 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Chemical Function
Softener and conditioner
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Sodium glycinate
E Number
E640ii
Food Category
flavor_enhancer
Frequently Asked Questions
Is Sodium Glycinate allowed in the EU?
Sodium Glycinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Glycinate do in cosmetics?
Sodium Glycinate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 6000-44-8.
Is Sodium Glycinate used outside cosmetics?
Sodium Glycinate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Glycinate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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SODIUM (ASTROCARYUM VULGARE/EUTERPE OLERACEAE/PALM) FRUIT/(ASTROCARYUM VULGARE/PALM) KERNEL/(ASTROCARYUM MURUMURU/BABASSU/BERTHOLLETIA EXCELSA/CARAPA GUIANENSIS/COCOA/FEVILLEA TRILOBATA/PASSIFLORA EDULIS/THEOBROMA GRANDIFLORUM) SEEDATE
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Cleansing, Surfactant - Cleansing
SODIUM BEHENOYL/COCOYL (ALANINE/ARGININE/ASPARAGINE/ASPARTIC ACID/GLUTAMIC ACID/GLYCINE/ISOLEUCINE/LEUCINE/LYSINE/METHIONINE/PHENYLALANINE/PROLINE/SERINE/THREONINE/TRYPTOPHAN/TYROSINE/VALINE)
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