NOAEL Studies Cosmetic Ingredient

Sodium 5-Nitroguaiacolate NOAEL Studies

INCI: ⛔ NO COSMETIC INCI ASSIGNED — NOT A COSMETIC INGREDIENT

CAS: 67233-85-6

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =0.3 mg/kg bw/day Dog oral: unspecified 365 days chronic/long term toxicity EFSA - 2009 - OutputID 1157 - clinical signs - systemic - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =0.7 mg/kg bw/day Dog oral: unspecified 365 days chronic/long term toxicity EFSA - 2009 - OutputID 1157 - clinical signs - systemic - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =13.6 mg/kg bw/day Rabbit - - reproduction toxicity EFSA - 2009 - OutputID 1157 - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =300 mg/kg bw/day Rat - - reproduction toxicity EFSA - 2009 - OutputID 1157 - body weight - systemic - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx ADI =0.003 mg/kg bw/day Consumers - - ADI EFSA - 2009 - OutputID 1157 - Consumers - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx ADI =0.003 mg/kg bw/day Consumers - - ADI EFSA - 2009 - OutputID 1157 - Consumers - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx ARfD =0.045 mg/kg bw/day Consumers - - ARfD EFSA - 2009 - OutputID 1157 - Consumers - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx ARfD =0.045 mg/kg bw/day Consumers - - ARfD EFSA - 2009 - OutputID 1157 - Consumers - Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. - doi:10.2903/j.efsa.2009.191r
ToxValDB_EFSA 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_EFSA NOAEL =0.3 mg/kg bw/day Dog oral chronic; 1 years chronic LONG_REF=EFSA (2009). Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. doi:10.2903/j.efsa.2009.191r.; TITLE=Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.; AUTHOR=EFSA; DOI=doi:10.2903/j.efsa.2009.191r; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2009; ORIGINAL_YEAR=2009; TOXICOLOGICAL_EFFECT=clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=EFSA_dup_-_15620322_15620323:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_df0770ecc50b792e12a05abc900349e5
ToxValDB_EFSA NOAEL =0.7 mg/kg bw/day Dog oral chronic; 1 years chronic LONG_REF=EFSA (2009). Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. doi:10.2903/j.efsa.2009.191r.; TITLE=Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.; AUTHOR=EFSA; DOI=doi:10.2903/j.efsa.2009.191r; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2009; ORIGINAL_YEAR=2009; TOXICOLOGICAL_EFFECT=clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=EFSA_dup_-_15620322_15620323:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_aa0ac17820753226f34508df9f6e889a
ToxValDB_EFSA NOAEL =13.6 mg/kg bw/day Rabbit oral - reproduction developmental LONG_REF=EFSA (2009). Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate. doi:10.2903/j.efsa.2009.191r.; TITLE=Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.; AUTHOR=EFSA; DOI=doi:10.2903/j.efsa.2009.191r; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2009; ORIGINAL_YEAR=2009; STUDY_GROUP=EFSA:15620324:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9bda5daea28a615ca2aa3c0a557ce15d
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier A1RBP9328O UNII - - - chemical {"approval_status":null,"molecular_formula":"C7H6NO4.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"A1RBP9328O"}
openFDA substances FDA UNII substance identifier A1RBP9328O UNII - - - chemical {"approval_status":null,"molecular_formula":"C7H6NO4.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"A1RBP9328O"}
openFDA substances FDA UNII substance identifier A1RBP9328O UNII - - - chemical {"approval_status":null,"molecular_formula":"C7H6NO4.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"A1RBP9328O"}
openFDA substances FDA UNII substance identifier A1RBP9328O UNII - - - chemical {"approval_status":null,"molecular_formula":"C7H6NO4.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"A1RBP9328O"}