Is Silver Hydroxide safe in cosmetics?
Silver Hydroxide has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
Silver Hydroxide
Also known as: Argentous oxide, Disilver monoxide, Disilver oxide, Silver oxide, Silver(I) oxide (+1 more)
INCI: SILVER HYDROXIDE
Silver Hydroxide (CAS 20667-12-3) is a cosmetic cosmetic ingredient functioning as Antimicrobial. NOAEL 30 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 20667-12-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Silver Hydroxide is classified GHS Danger (H271, H272, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antimicrobial
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not specifically restricted; general cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Silver Hydroxide.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Silver Hydroxide across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Surface modifier
Expert Verdict
Expert safety assessment and concern-level summary for Silver Hydroxide.
Known Synonyms
Argentous oxide
Disilver monoxide
Disilver oxide
Silver oxide
Silver(I) oxide
EINECS No.: 243-957-1
Chemical Function
Biocide
Surface modifier
Regulatory Lists
active_ingredient; Europe; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
22
Frequently Asked Questions
Is Silver Hydroxide allowed in the EU?
Silver Hydroxide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Silver Hydroxide do in cosmetics?
Silver Hydroxide functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 20667-12-3.
Is Silver Hydroxide used outside cosmetics?
Silver Hydroxide also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Silver Hydroxide have different safety status in cosmetics vs industrial chemicals?
Silver Hydroxide is classified GHS Danger (H271, H272, H318, H400, H410) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Silver Hydroxide compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Chemical family
Antimicrobial agent
SILICON
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Abrasive
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